Trabalho de Conclusão de Curso de Especialização
Influência do controle virológico e da terapia antirretroviral sobre a força muscular respiratória em sujeitos com HIV
Fecha
2017-08-09Autor
Righi, Geovana de Almeida
Institución
Resumen
Since the introduction of the antiretroviral therapy (ART), the life expectancy of Human Immunodeficiency Virus (HIV) carriers has increased, thus, being the viral load monitoring a tool for the progression evaluation of the HIV. The respiratory muscle weakness already has been cited in previous studies and it is present in this population, although there are no reports comparing different levels of viral load. The objective of this study was to evaluate the influence of the viral control and the use of the antiretroviral therapy on respiratory muscle strength in HIV patients. Cross-sectional study, 60 patients with HIV, both sexes, subdivided in three groups: with ART and load viral not detectable (AGVL-; n=20); with ART and load viral detectable (AGVL+; n=20); without ART and load viral detectable (nAGVL+; n=20). The respiratory muscle strength was measured through digital manovacuometer. The load viral was lower in the AGVL+ than in nAGVL+, since the AGVL- has showed load viral not detectable. The counting of T-CD4 cells was bigger in AGVL- than the others. The groups AGVL+ and nAGVL+ demonstrated inspiratory muscle weakness (MIP<70% of the predicted). The patients group using ART with load viral not detectable showed bigger expiratory muscle strength and were not classified with inspiratory muscle weakness. These favorable effects of the ART and of lower load viral may result in better functional outcomes.