Tesis
Suscetibilidade antimicrobiana de Staphylococcus spp. isolados de cães com pioderma superficial
Fecha
2013-03-01Registro en:
SILVA, Ana Paula da. Antimicrobial susceptibility of Staphylococcus spp.
isolated from canine superficial pyoderma. 2013. 37 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2013.
Autor
Silva, Ana Paula da
Institución
Resumen
Superficial pyoderma is the bacterial infection of the epidermis and hair follicle
and is a common skin disease in dogs. The main etiological agents involved are bacteria
of the Staphylococcus genus. This skin disease represents one of the main indications
for antimicrobial therapy by small animal practitioners, a procedure usually performed
empirically. The emergence of multidrug-resistant staphylococci species in skin
infections has been reported in many countries and implies difficulties in the treatment.
This study aimed to determine the antimicrobial susceptibility and evaluate the presence
of multidrug resistance in 154 isolates of Staphylococcus spp. from skin lesions of dogs
with superficial pyoderma that were assisted by the Veterinary Dermatology Service at
the Hospital Veterinário Universitário (HVU) of the Universidade Federal de Santa
Maria (UFSM). After bacterial culture and identification, the isolates were tested for
antimicrobial susceptibility, and the results showed high rates of resistance to
amoxicillin (60.4%) and penicillin G (60.4%), moderate resistance to potentiated
sulfonamides (29.9%), enrofloxacin (20.1%), ciprofloxacin (18.8%) and azithromycin
(17.5%), and low percentages of resistance to the amoxicillin and clavulanic acid
association (1.9%), cephalexin (1.9 %), cefadroxil (1.9%) and vancomycin (0.6%). The
multidrug resistance was detected in 23.4% (11/154) and the methicillin resistance in
5.8% (9/154) of the samples. It may be concluded that the Staphylococcus spp. isolates
present high susceptibility to key antimicrobials used in the treatment of superficial
pyodermas in dogs at the HVU-UFSM, such as cephalexin and the amoxicillin and
clavulanic acid association, confirming the preference for these drugs when treating
dogs with this disorder. The susceptibility of the isolates to fluoroquinolones, also
recommended in the literature as an alternative in the treatment of pyodermas, allows
suggesting that such drugs should not be considered in the empirical selection. The
identification of multidrug-resistant Staphylococcus spp. in the studied canine
population justifies periodic and regional bacteriological tests of skin lesions in dogs
with superficial pyoderma, to minimize bacterial resistance, possible therapeutic failures
and also motivates wise use of antimicrobial therapy.