Universidad Mayor (Chile): últimos ingresos
Mostrando ítems 301-320 de 7087
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Development of "on-demand" thermo-responsive hydrogels for anti-cancer drugs sustained release: Rational design, in silico prediction and in vitro validation in colon cancer models
(ELSEVIER, 2021-12)A rational design accurate based on the use of Statistical Design of the Experiments (DoE) and Molecular Dynamics Simulations Studies allows the prediction and the understanding of thermo-responsive hydrogels prepared ... -
Testing the Test: A Comparative Study of Marine Microbial Corrosion under Laboratory and Field Conditions
(AMER CHEMICAL SOC, 2021-06-25)Microbially influenced corrosion (MIC) is an aggressive type of corrosion that occurs in aquatic environments and is sparked by the development of a complex biological matrix over a metal surface. In marine environments, ... -
Development of a PHBV nanoparticle as a peptide vehicle for NOD1 activation
(TAYLOR & FRANCIS LTD, 2021-06-08)NOD1 is an intracellular receptor that, when activated, induces gene expression of pro-inflammatory factors promoting macrophages and neutrophils recruitment at the infection site. However, iE-DAP, the dipeptide agonist ... -
ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks
(OXFORD UNIV PRESS INC, 2021-04-28)Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ... -
Exploring mindfulness in/as education from a Heideggerian perspective
(OXFORD UNIV PRESS, 2021-07-17)Over the past decade or so within this journal, there have been critical debates concerning the role of mindfulness within education, the influence of neoliberalism on education in general and well-being interventions ... -
CD73 Ectonucleotidase Restrains CD8+T Cell Metabolic Fitness and Anti-tumoral Activity 1 of 1 CD73 Ectonucleotidase Restrains CD8+T Cell Metabolic Fitness and Anti-tumoral Activity
(FRONTIERS MEDIA SA, 2021-02-18)CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ... -
Energy, Economic, and Environmental Performance of a Single-Family House in Chile Built to Passivhaus Standard
(MDPI, 2021-02-26)The energy consumption of buildings accounts for 22% of total global energy use and 13% of global greenhouse gas emissions. In this context, this study aims to evaluate the energy, economic, and environmental performance ... -
Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
(BMJ PUBLISHING GROUP, 2021-08-29)Introduction Grip strength has been associated with chronic diseases and mortality. However, current evidence of the association between grip strength and incident type 2 diabetes mellitus (T2DM) is controversial. The aim ... -
Molecular Weight Enables Fine-Tuning the Thermal and Dielectric Properties of Polymethacrylates Bearing Sulfonyl and Nitrile Groups as Dipolar Entities
(MDPI, 2021-02-22)In this work, polymethacrylates containing sulfonyl and nitrile functional groups were successfully prepared by conventional radical polymerization and reversible addition-fragmentation chain-transfer polymerization (RAFT). ... -
Novel Polyelectrolytes Obtained by Direct Alkylation and Ion Replacement of a New Aromatic Polyamide Copolymer Bearing Pyridinyl Pendant Groups
(MDPI, 2021-07-05)The following work shows, for the first time, the synthesis and characterization of a new family of polyelectrolytes, along with their preliminary assessments in terms of desalin water treatment. These materials fall into ... -
Reducing police occupational needle stick injury risk following an interactive training: the SHIELD cohort study in Mexico
(MDPI, 2021-05-14)Objective At a time of unprecedented attention to the public health impact of policing, it is imperative to understand the role of occupational safety in shaping officer behaviours. We assessed the longitudinal impact of ... -
Monitoring Chilecomadia valdiviana (Lepidoptera: Cossidae) Using Sex Pheromone-Baited Traps in Apple Orchards in Chile
(MDPI, 2021-07-07)Simple Summary A series of experiments were carried out to evaluate the efficacy of trap type, sex pheromone (Z7,Z10-16:Ald) dose, and trap height on attraction to males of Chilecomadia valdiviana (Philippi) (Lepidoptera: ... -
Epidemiology of Dog Bite Incidents in Chile: Factors Related to the Patterns of Human-Dog Relationship
(MDPI, 2021-02-03)Dog bites are a major public health problem throughout the world. The main consequences for human health include physical and psychological injuries of varying proportions, secondary infections, sequelae, risk of transmission ... -
Characterization of the Variables Related to Reports of Death Due to Canine Bites in Scientific Articles during the Years 2013-2017: A Systematic Review
(MDPI, 2021-10-02)Simple Summary Dog bites are a major public health problem throughout the world. The main consequences for human health include physical and psychological injuries of varying proportions, secondary infections, sequelae, ... -
Systematic Review: Comparison of the Main Variables of Interest in Publications of Canine Bite Accidents in the Written Press, Gray and Scientific Literature in Chile and Spain, between the Years 2013 and 2017
(MDPI, 2021-04-06)Dog bites are a major public health problem throughout the world. The different types of information sources that exist in relation to this issue are influencing decision making to control and prevent these incidents. For ... -
In Vivo Antitumor Effect against Murine Cells of CT26 Colon Cancer and EL4 Lymphoma by Autologous Whole Tumor Dead Cells
(HINDAWI LTD, 2021-03-14)Active immunotherapy against cancer is based on immune system stimulation, triggering efficient and long-lasting antigen-specific immune responses. Immunization strategies using whole dead cells from tumor tissue, containing ... -
Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjogren's syndrome
(OXFORD UNIV PRESS, 2021-05-25)Objective. Altered homeostasis of salivary gland (SG) epithelial cells in Sjogren's syndrome (SS) could be the initiating factor that leads to inflammation, secretory dysfunction and autoimmunity. Autophagy is an important ... -
Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjo¨gren's syndrome
(ELSEVIER, 2021-07-23)Relevant reviews highlight the association between dysfunctional mitochondria and inflammation, but few studies address the contribution of mitochondria and mitochondria-endoplasmic reticulum (ER) contact sites (MERCs) to ... -
Municipal police support for harm reduction services in officer-led referrals of people who inject drugs in Tijuana, Mexico
(BMC, 2021-08-01)Background Police constitute a structural determinant of health and HIV risk of people who inject drugs (PWID), and negative encounters with law enforcement present significant barriers to PWID access to harm reduction ...