Mostrando ítems 2821-2840 de 7087

    • Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2 

      González-Manan, D. [Univ Mayor, Fac Ciencias, Nucleo Quim & Bioquim, Santiago, Chile]; Echeverria, F.; Valenzuela, R.; Espinosa, A.; Bustamante, A.; Alvarez, D.; Ortiz, M.; Soto-Alarcón, S. A.; Videla, L. A. (ELSEVIER SCIENCE INC, 2019)
      High-fat diet (HFD)-fed mice show obesity with development of liver steatosis and a proinflammatory state without establishing an inflammatory reaction. The aim of this work was to assess the hypothesis that eicosapentaenoic ...
    • Cultural Collectivism and Tightness Moderate Responses to Norm Violators: Effects on Power Perception, Moral Emotions, and Leader Support 

      Figueiredo, Ana [Univ Mayor, Santiago, Chile]; Stamkou, Eftychia; van Kleef, Gerben A.; Homan, Astrid C.; Gelfand, Michele J.; van de Vijver, Fons J. R.; van Egmond, Marieke C.; Boer, Diana; Phiri, Natasha; Ayub, Nailah; Kinias, Zoe; Cantarero, Katarzyna; Treister, Dorit Efrat; Hashimoto, Hirofumi; Hofmann, Eva B.; Lima, Renata P.; Lee, I-Ching (SAGE PUBLICATIONS INC, 2019)
      Responses to norm violators are poorly understood. On one hand, norm violators are perceived as powerful, which may help them to get ahead. On the other hand, norm violators evoke moral outrage, which may frustrate their ...
    • Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation 

      Rojas-Rivera, Diego [Univ Mayor, Fac Sci, Ctr Integrat Biol]; Dondelinger, Yves; Delanghe, Tom; Priem, Dario; Wynosky-Dolfi, Meghan A.; Sorobetea, Daniel; Giansanti, Piero; Roelandt, Ria; Gropengiesser, Julia; Ruckdeschel, Klaus; Savvides, Savvas N.; Heck, Albert J. R.; Vandenabeele, Peter; Brodsky, Igor E.; Bertrand, Mathieu J. M. (NATURE PUBLISHING GROUP, 2019)
      RIPK1 regulates cell death and inflammation through kinase-dependent and -independent mechanisms. As a scaffold, RIPK1 inhibits caspase-8-dependent apoptosis and RIPK3/MLKL-dependent necroptosis. As a kinase, RIPK1 ...
    • Historical trends in the grade of onset and sequence of cigarette, alcohol, and marijuana use among adolescents from 1976-2016: Implications for"Gateway"patterns in adolescence 

      Keyes, Katherine M. [Univ Mayor, Ctr Res Soc & Hlth, Santiago, Chile]; Rutherford, Caroline; Miech, Richard (ELSEVIER IRELAND LTD, 2019)
      Introduction: In the past decade, marijuana use prevalence among adolescents has remained relatively steady while cigarette and alcohol prevalence has declined. We examined historical trends in: average grade of onset of ...
    • Mitochondria in Developmental and Adult Neurogenesis 

      Arrazola, Macarena S. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol, Santiago, Chile]; Andraini, Trinovita; Szelechowski, Marion; Mouledous, Lionel; Arnaune-Pelloquin, Laetitia; Davezac, Noelie; Belenguer, Pascale; Rampon, Claire; Miquel, Marie-Christine (SPRINGER, 2019)
      Generation of new neurons is a tightly regulated process that involves several intrinsic and extrinsic factors. Among them, a metabolic switch from glycolysis to oxidative phosphorylation, together with mitochondrial ...
    • A typology of prescription drug monitoring programs: a latent transition analysis of the evolution of programs from 1999 to 2016 

      Castillo-Carniglia, Alvaro [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr, Santiago, Chile]; Smith, Nathan; Martins, Silvia S.; Kim, June; Rivera-Aguirre, Ariadne; Fink, David S.; Henry, Stephen G.; Mooney, Stephen J.; Marshall, Brandon D. L.; Davis, Corey; Cerda, Magdalena (WILEY, 2019)
      Background and aims Prescription drug monitoring programs (PDMP), defined as state-level databases used in the United States that collect prescribing information when controlled substances are dispensed, have varied ...
    • A Prunus persica genome-wide RNA-seq approach uncovers major differences in the transcriptome among chilling injury sensitive and non-sensitive varieties 

      Vizoso, Paula [Univ Mayor, Ctr Propagac & Conservac Vegetal, Santiago, Chile]; Nilo-Poyanco, Ricardo [Univ Mayor, Fac Ciencias, Escuela Biotecnol, Santiago, Chile]; Sanhueza, Dayan; Balic, Ivan; Meneses, Claudio; Orellana, Ariel; Campos-Vargas, Reinaldo (WILEY, 2019)
      Chilling injury represents a major constrain for crops productivity. Prunus persica, one of the most relevant rosacea crops, have early season varieties that are resistant to chilling injury, in contrast to late season ...
    • Ablation of brainstem C1 neurons improves cardiac function in volume overload heart failure 

      Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Díaz, Hugo S.; Lucero, Claudia; Arce-Alvarez, Alexis; Oliveira, Luiz M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Marcus, Noah J.; Alcayaga, Julio; Del Rio, Rodrigo (PORTLAND PRESS LTD, 2019)
      Activation of the sympathetic nervous system is a hallmark of heart failure (HF) and is positively correlated with disease progression. Catecholaminergic (C1) neurons located in the rostral ventrolateral medulla (RVLM) are ...
    • Age, period and cohort effects in frequent cannabis use among US students: 1991-2018 

      Keyes, Katherine M. [Univ Mayor, Ctr Res Soc & Hlth, Santiago, Chile]; Hamilton, Ava D.; Jang, Joy Bohyun; Patrick, Megan E.; Schulenberg, John E. (WILEY, 2019)
      Background and Aims As the legal status of cannabis changes across the United States and modes of administration expand, it is important to examine the potential impact on adolescent cannabis use. This study aimed to assess ...
    • Recent increases in depressive symptoms among US adolescents: trends from 1991 to 2018 

      Keyes, Katherine M. [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr, Santiago, Chile]; Gary, Dahsan; O'Malley, Patrick M.; Hamilton, Ava; Schulenberg, John (SPRINGER HEIDELBERG, 2019)
      BackgroundMental health problems and mental health related mortality have increased among adolescents, particularly girls. These trends have implications for etiology and prevention and suggest new and emerging risk factors ...
    • California's comprehensive background check and misdemeanor violence prohibition policies and firearm mortality 

      Castillo-Carniglia, Alvaro [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr]; Kagawa, Rose M. C.; Cerda, Magdalena; Crifasi, Cassandra K.; Vernick, Jon S.; Webster, Daniel W.; Wintemute, Garen J. (ELSEVIER SCIENCE INC, 2019)
      Purpose: In 1991, California implemented a law that mandated a background check for all firearm purchases with limited exceptions (comprehensive background check or CBC policy) and prohibited firearm purchase and possession ...
    • MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca2+ communication: a dead end in cancer cells 

      Silva-Pavez, Eduardo [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Ahumada-Castro, Ulises [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Lovy, Alenka; Pardo, Evelyn; Molgo, Jordi; Cardenas, César (TAYLOR & FRANCIS INC, 2019)
      The interruption of endoplasmic reticulum (ER)-mitochondrial Ca2+ communication induces a bioenergetic crisis characterized by an increase of MTOR-independent AMPK-dependent macroautophagic/autophagic flux, which is not ...
    • Experimental quantum tomography assisted by multiply symmetric states in higher dimensions 

      Jimenez, O. [Univ Mayor, Fac Ciencias, Ctr Opt & Informac Cuant]; Martínez, D.; Solis-Prosser, M. A.; Canas, G.; Delgado, A.; Lima, G. (AMER PHYSICAL SOC, 2019)
      High-dimensional quantum information processing has become a mature field of research with several different approaches being adopted for the encoding of D-dimensional quantum systems. Such progress has fueled the search ...
    • Autophagy as a Homeostatic Mechanism in Response to Stress Conditions in the Central Nervous System 

      Geronimo-Olvera, Cristián [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Massieu, Lourdes (SPRINGER, 2019)
      Autophagy is considered a major bulk degradation system that helps cells to counteract different intracellular and extracellular stress signals. Several protein complexes integrate multiple signals in order to activate ...
    • Global ecological predictors of the soil priming effect 

      Abades, Sebastián [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Bowker, Matthew A. [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Bastida, Felipe; Bastidal, Felipe; Garcia, Carlos; Fierer, Noah; Eldridge, David J.; Alfaro, Fernando D.; Berhe, Asmeret Asefaw; Cutler, Nick A.; Gallardo, Antonio; Garcia-Velazquez, Laura; Hart, Stephen C.; Hayese, Patrick E.; Hernández, Teresa; Hseu, Zeng-Yei; Jehmlich, Nico; Kirchmair, Martin; Lambers, Hans; Neuhauser, Sigrid; Pena-Ramírez, Víctor M.; Pérez, Cecilia A.; Reed, Sasha C.; Santos, Fernanda; Siebe, Christina; Sullivan, Benjamin W.; Trivedi, Pankaj; Vera, Alfonso; Williams, Mark A.; Moreno, JoséLuis; Delgado-Baquerizo, Manuel (NATURE PUBLISHING GROUP, 2019)
      Identifying the global drivers of soil priming is essential to understanding C cycling in terrestrial ecosystems. We conducted a survey of soils across 86 globally-distributed locations, spanning a wide range of climates, ...
    • Bacterial community structure in a sympagic habitat expanding with global warming: brackish ice brine at 85-90 degrees N 

      Trefault, Nicole [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Santiago, Chile]; Alfaro, Fernando D. [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Santiago, Chile]; Fernández-Gómez, Beatriz; Diez, Beatriz; Polz, Martin F.; Ignacio Arroyo, Jose; Marchandon, German; Sanhueza, Cynthia; Farias, Laura; Marquet, Pablo A.; Molina-Montenegro, Marco A.; Sylvander, Peter; Snoeijs-Leijonmalm, Pauline (NATURE PUBLISHING GROUP, 2019)
      Larger volumes of sea ice have been thawing in the Central Arctic Ocean (CAO) during the last decades than during the past 800,000 years. Brackish brine (fed by meltwater inside the ice) is an expanding sympagic habitat ...
    • What is the temporal extension of edge effects on tree growth dynamics? A dendrochronological approach model using Scleronema micranthum (Ducke) Ducke trees of a fragmented forest in the Central Amazon 

      Venegas-González, Alejandro [Univ Mayor, Fac Ciencias, Escuela Ingn Forestal, Ctr Observ Tierra Hemera]; Albiero-Junior, Alci; Botosso, Paulo César; Alejandro Roig, Fidel; Campana Camargo, JoséLuis; Tomazello-Filho, Mario (ELSEVIER SCIENCE BV, 2019)
      Although the Amazon Forest comprises the world's largest rainforest, providing fundamental ecosystem services to human well-being, vicissitudes imposed by deforestation, climate change, widespread use of fire and development ...
    • Uptake and persistence of bacterial magnetite magnetosomes in a mammalian cell line: Implications for medical and biotechnological applications 

      dos Santos, Adriana Lopes [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Huechuraba, Chile]; Cypriano, Jefferson; Werckmann, Jacques; Vargas, Gabriele; Silva, Karen T.; Leao, Pedro; Almeida, Fernando P.; Bazylinski, Dennis A.; Farina, Marcos; Lins, Ulysses; Abreu, Fernanda (PUBLIC LIBRARY SCIENCE, 2019)
      Magnetotactic bacteria biomineralize intracellular magnetic nanocrystals surrounded by a lipid bilayer called magnetosomes. Due to their unique characteristics, magnetite magnetosomes are promising tools in Biomedicine. ...
    • Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus 

      Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Lucero, Claudia; Díaz, Hugo S.; Schwarz, Karla G.; Pereyra, Katherin V.; Arce-Alvarez, Alexis; López, Nicolás A.; Martínez, Milka; Inestrosa, Nibaldo C.; Del Rio, Rodrigo (IMPACT JOURNALS LLC, 2019)
      Age represents the highest risk factor for death due to cardiovascular disease. Heart failure (HF) is the most common cardiovascular disease in elder population and it is associated with cognitive impairment (CI), diminishing ...
    • Mental illness, drinking, and the social division and structure of labor in the United States: 2003-2015 

      Keyes, Katherine M. [Univ Mayor, Ctr Res Soc & Hlth, Santiago, Chile]; Prins, Seth J.; McKetta, Sarah; Platt, Jonathan; Muntaner, Carles; Bates, Lisa M. (WILEY, 2019)
      Background We draw on a relational theoretical perspective to investigate how the social division and structure of labor are associated with serious and moderate mental illness and binge and heavy drinking. Methods The ...