Artículos de revistas
Some effects of cimetidine on the reproductive organs of rats
Fecha
1987-01-01Registro en:
General Pharmacology: Vascular System, v. 18, n. 2, p. 197-199, 1987.
0306-3623
10.1016/0306-3623(87)90250-3
WOS:A1987G614900016
2-s2.0-0023130970
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
1. The development of genital organs of rats chronically treated with cimetidine showed that the drug may present anti-androgenic activity. 2. This treatment did not alter the sensitivity of vas deferens to noradrenaline, but increased their sensitivity to BaCl2. 3. In the male reproductive system, cimetidine must have peripheral actions apart from the central ones observed after chronic treatment.