Artículos de revistas
Dimensional correlates of poor insight in obsessive-compulsive disorder
Progress in Neuro-Psychopharmacology and Biological Psychiatry, v. 35, n. 7, p. 1677-1681, 2011.
University of Heidelberg
Yale University School of Medicine
Universidade Estadual Paulista (UNESP)
Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)
Universidade de São Paulo (USP)
Background: Cross-sectional studies have associated poor insight in patients with obsessive-compulsive disorder (OCD) with increased OCD symptom severity, earlier age of onset, comorbid depression, and treatment response. The goal of this current study was to examine the relationship between dimensions of OCD symptomatology and insight in a large clinical cohort of Brazilian patients with OCD. We hypothesized that poor insight would be associated with total symptom severity as well as with hoarding symptoms severity, specifically. Methods: 824 outpatients underwent a detailed clinical assessment for OCD, including the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS), the Brown Assessment of Beliefs Scale (BABS), a socio-demographic questionnaire, and the Structured Clinical Interview for axis I DSM-IV disorders (SCID-P). Tobit regression models were used to examine the association between level of insight and clinical variables of interest. Results: Increased severity of current and worst-ever hoarding symptoms and higher rate of unemployment were associated with poor insight in OCD after controlling for current OCD severity, age and gender. Poor insight was also correlated with increased severity of current OCD symptoms. Conclusion: Hoarding and overall OCD severity were significantly but weakly associated with level of insight in OCD patients. Further studies should examine insight as a moderator and mediator of treatment response in OCD in both behavioral therapy and pharmacological trials. Behavioral techniques aimed at enhancing insight may be potentially beneficial in OCD, especially among patients with hoarding. © 2011.
Showing items related by title, author, creator and subject.
Impulsive compulsivity in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome Kashyap, Himani; Fontenelle, Leonardo F.; Miguel, Euripedes C.; Ferrão, Ygor A.; Torres, Albina Rodrigues; Shavitt, Roseli G.; Ferreira-Garcia, Rafael; Do Rosário, Maria C.; Yücel, Murat
Impulsive compulsivity in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome University of Melbourne and Melbourne Health; Federal University of Rio de Janeiro; D'Or Institute for Research and Education; Universidade de São Paulo (USP); Health Sciences Federal University of Porto Alegre; Universidade Estadual Paulista (UNESP) (2012-09-01)Although traditionally obsessive-compulsive disorder (OCD) and impulse control disorders (ICD) have represented opposing ends of a continuum, recent research has demonstrated a frequent co-occurrence of impulsive and ...
Jakubovski, Ewgeni; Pittenger, Christopher; Torres, Albina Rodrigues; Fontenelle, Leonardo Franklin; do Rosario, Maria Conceicao; Ferrão, Ygor Arzeno; de Mathis, Maria Alice; Miguel, Euripedes Constantino; Bloch, Michael H.