DNA viruses in human cancer: An integrated overview on fundamental mechanisms of viral carcinogenesis

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:37:04Z
dc.date.available2014-05-20T13:37:04Z
dc.date.created2014-05-20T13:37:04Z
dc.date.issued2007-03-18
dc.identifierCancer Letters. Clare: Elsevier B.V., v. 247, n. 2, p. 182-196, 2007.
dc.identifier0304-3835
dc.identifierhttp://hdl.handle.net/11449/12797
dc.identifier10.1016/j.canlet.2006.05.010
dc.identifierWOS:000244995800002
dc.identifier5240998569868081
dc.description.abstractThe first experimental data suggesting that neoplasm development in animals might be influenced by infectious agents were published in the early 1900s. However, conclusive evidence that DNA viruses play a role in the pathogenesis of some human cancers only emerged in the 1950s, when Epstein-Barr virus (EBV) was discovered within Burkitt lymphoma cells. Besides EBV, other DNA viruses consistently associated with human cancers are the hepatitis B virus (HBV), human papillomavirus (HPV), and Kaposi sarcoma herpesvirus (KSHV). Although each virus has unique features, it is becoming clearer that all these oncogenic agents target multiple cellular pathways to support malignant transformation and tumor development. (c) 2006 Elsevier B.V.. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationCancer Letters
dc.relation6.491
dc.relation2,350
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectviral carcinogenesis
dc.subjectDNA viruses
dc.subjectcancer
dc.subjectEpstein-Barr virus
dc.subjectKaposi's sarcoma-associated virus
dc.subjecthuman papillomavirus
dc.subjectsimian virus 40 virus
dc.subjecthepatitis B virus
dc.titleDNA viruses in human cancer: An integrated overview on fundamental mechanisms of viral carcinogenesis
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución