Artículo de revista
Resultados del tratamiento del cáncer de mama, Programa Nacional de Cáncer del Adulto
Fecha
2017Registro en:
Rev Med Chile 2017; 145: 1507-1513
07176163
00349887
10.4067/s0034-98872017001201507
Autor
Castillo, César del
Cabrera C., M. Elena
Derio P., Lea
Gaete V., Fancy
Cavada Chacón, Gabriel
Institución
Resumen
Background: Breast cancer is the most common malignant tumor in women
in the world. In 2005, it was incorporated to the Explicit Guaranties Health
System (GES) in Chile. Aim: To describe the demographic and clinical characteristics
of breast cancer patients and to determine the effect of incorporating
these women to GES. Material and Methods: Medical records of 5,119 women
with breast cancer aged 59 ± 14 years, attended at six public hospitals between
2000 and 2010 were reviewed. Median follow up was 87 months (range 1-182).
Mortality was assessed using death certificates obtained at the National Identification
Registry. Results: Sixty six percent of women were in stage I-II, 29% in
stage III and 5% in stage IV. Surgery was performed in 4023/5119 cases (79%),
adyuvant radiotherapy in 3627/4517 cases (80%), chemotherapy in 3,204/3,424
cases (94%) and hormone therapy in 1,695/2,375 cases (71%). Between 2000
and 2010, there was a significant increase in the proportion of cases in stage I,
from 8% to 25%, (p < 0.01). Overall survival (OS) increased 1% per year, since
the beginning of GES system (p = 0.024). Five year OS was 75.1%. The figures
for Stage I, II, III and IV were 93, 84, 62 and 27% respectively (p < 0.01). Patients
without lymph node involvement and who were not triple negative, had a
significantly better OS. Conclusions: There was a significant increase in stage I
cases, and a 1% per year OS improvement after GES system started, compared
with the previous period.