dc.creatorCofré, Fernanda
dc.creatorVillarroel, Milena
dc.creatorCastellón, Loreto
dc.creatorSantolaya de Pablo, María Elena
dc.date.accessioned2019-03-18T11:53:35Z
dc.date.available2019-03-18T11:53:35Z
dc.date.created2019-03-18T11:53:35Z
dc.date.issued2015
dc.identifierRevista Chilena de Infectologia, Volumen 32, Issue 4, 2018, Pages 458-463
dc.identifier07161018
dc.identifier10.4067/S0716-10182015000500015
dc.identifierhttps://repositorio.uchile.cl/handle/2250/166672
dc.description.abstract© 2015, Sociedad Chilena de Infectologia. All rights reserved.The fungi of the order Mucorales cause mucormycosis, which usually presents as an invasive fungal disease with rapid angioinvasion in immunocompromised patients. Rhinocerebral is the most common presentation. The lipid formulations of amphotericin B are used as primary treatment in invasive mucormycosis; the combined use of posaconazole could allow a reduction in the dose of amphotericin B improving tolerance and adherence to treatment. Caspofungin and amphotericin B association has been shown to be synergistic in vitro and effective in murine models. We present the case of a preschool patient that during the debut of acute lymphoblastic leukemia developed a rhinocerebral mucormycosis successfully responding to antifungal treatment with the combination of liposomal amphotericin and caspofungin.
dc.languageen
dc.publisherSociedad Chilena de Infectologia
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceRevista Chilena de Infectologia
dc.subjectEchinocandin
dc.subjectFebrile neutropenia
dc.subjectMucormycosis
dc.subjectPosaconazole
dc.titleSuccessful treatment of a persistent rhino-cerebral mucormycosis in a pediatric patient with a debut of acute lymphoblastic leukemia Tratamiento exitoso de una mucormicosis rinocerebral persistente en un paciente pediátrico durante el debut de una leucemi
dc.typeArtículos de revistas


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