dc.creator | Tampier, Lutske | |
dc.creator | Quintanilla González, María Elena | |
dc.date.accessioned | 2019-03-11T12:57:39Z | |
dc.date.available | 2019-03-11T12:57:39Z | |
dc.date.created | 2019-03-11T12:57:39Z | |
dc.date.issued | 2009 | |
dc.identifier | Addiction Biology, Volumen 14, Issue 3, 2018, Pages 276-282 | |
dc.identifier | 13556215 | |
dc.identifier | 13691600 | |
dc.identifier | 10.1111/j.1369-1600.2009.00147.x | |
dc.identifier | http://repositorio.uchile.cl/handle/2250/164791 | |
dc.description.abstract | This study examined the effect of concurrent presentation of a highly palatable saccharin solution on ethanol consumption during the acquisition or maintenance of ethanol drinking by high-alcohol-drinking (UChB) rats. Rats were exposed to ethanol (10% v/v) and water under a home cage, two-bottle, free-choice regimen with unlimited access for 24 hours/day. After 7 days (acquisition) of ethanol exposure, a third bottle containing saccharin (0.2% w/v) was concomitantly offered for an additional seven consecutive days, and the same process was repeated after 3 months (maintenance) of ethanol exposure. We found that concurrent saccharin intake significantly reduced ethanol intake by UChB rats after 7 days of ethanol exposure indicating that preference for sweet taste tends to override the preference for ethanol. However, the concurrent saccharin presentation to rats after 3 months of stable ethanol consumption did not reduce ethanol intake, whereas their saccharin consumption reached polydi | |
dc.language | en | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Addiction Biology | |
dc.subject | Alcohol preference | |
dc.subject | Ethanol consumption | |
dc.subject | Ethanol-sensitized rats | |
dc.subject | High alcohol drinking | |
dc.subject | Saccharin on ethanol intake | |
dc.subject | UChB rats | |
dc.title | Effect of concurrent saccharin intake on ethanol consumption by high-alcohol-drinking (UChB) rats | |
dc.type | Artículos de revistas | |