dc.creator | Sir Petermann, Teresa | |
dc.creator | Maliqueo Yevilao, Manuel | |
dc.creator | Codner Dujovne, Ethel | |
dc.creator | Echiburú López, Bárbara | |
dc.creator | Crisosto King, Nicolás | |
dc.creator | Pérez, Virginia | |
dc.creator | Pérez Bravo, Francisco | |
dc.creator | Cassorla Goluboff, Fernando | |
dc.date.accessioned | 2019-03-11T12:55:02Z | |
dc.date.available | 2019-03-11T12:55:02Z | |
dc.date.created | 2019-03-11T12:55:02Z | |
dc.date.issued | 2007 | |
dc.identifier | Journal of Clinical Endocrinology and Metabolism, Volumen 92, Issue 12, 2018, Pages 4637-4642 | |
dc.identifier | 0021972X | |
dc.identifier | 0021972X | |
dc.identifier | 10.1210/jc.2007-1036 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/164441 | |
dc.description.abstract | Context: Polycystic ovary syndrome (PCOS) is a familial endocrine-metabolic dysfunction, increasingly recognized in adolescent girls with hyperandrogenism. However, it is difficult to establish whether the metabolic abnormalities described in PCOS are present before the onset of hyperandrogenism. In children, a strong association of adiponectin levels with metabolic parameters of insulin resistance has been described. Objective: The objective of the study was to evaluate adiponectin serum concentrations and metabolic parameters in prepubertal and pubertal daughters of women with PCOS to identify girls with increased metabolic risk. Design: Fifty-three prepubertal and 22 pubertal (Tanner stages II-V) daughters of PCOS women (PCOSd) and 32 prepubertal and 17 pubertal daughters of control women (Cd) were studied. In both groups, an oral glucose tolerance test was performed with measurement of glucose and insulin. Adiponectin, leptin, C-reactive protein, SHBG, sex steroids, and lipids were | |
dc.language | en | |
dc.publisher | Endocrine Society | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Journal of Clinical Endocrinology and Metabolism | |
dc.subject | Endocrinology, Diabetes and Metabolism | |
dc.subject | Biochemistry | |
dc.subject | Endocrinology | |
dc.subject | Clinical Biochemistry | |
dc.subject | Biochemistry (medical) | |
dc.title | Early metabolic derangements in daughters of women with polycystic ovary syndrome | |
dc.type | Artículos de revistas | |