Evidence for an antihyperalgesic effect of venlafaxine in vincristine-induced neuropathy in rat

dc.creatorMarchand, Fabien
dc.creatorAlloui, Abdelkrim
dc.creatorPelissier Serrano, Teresa
dc.creatorHernández, Alejandro
dc.creatorAuthier, Nicolas
dc.creatorAlvarez, Pedro
dc.creatorEschalier, Alain
dc.creatorArdid, Denis
dc.date.accessioned2019-01-29T17:51:44Z
dc.date.available2019-01-29T17:51:44Z
dc.date.created2019-01-29T17:51:44Z
dc.date.issued2003
dc.identifierBrain Research, Volumen 980, Issue 1, 2018, Pages 117-120
dc.identifier00068993
dc.identifier10.1016/S0006-8993(03)02946-9
dc.identifierhttps://repositorio.uchile.cl/handle/2250/163554
dc.description.abstractVenlafaxine, a new antidepressant with fewer side effects, could be of interest to reduce neuropathic pain following antineoplasic drug treatment. In the present study, we demonstrated that venlafaxine inhibits hyperalgesia in a new rat model of neuropathy induced by the antineoplasic drug vincristine, and exerts its effect preferentially via supraspinal and spinal mechanisms. © 2003 Elsevier B.V. All rights reserved.
dc.languageen
dc.publisherElsevier
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceBrain Research
dc.subjectAntidepressants
dc.subjectAntineoplasic drug
dc.subjectC reflex
dc.subjectNeuropathic pain
dc.subjectPaw pressure
dc.subjectRat
dc.subjectVenlafaxine
dc.titleEvidence for an antihyperalgesic effect of venlafaxine in vincristine-induced neuropathy in rat
dc.typeArtículo de revista


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