Effects of aminotriazole on ethanol, water, and food intake and on brain catalase in UChA and UChB rats

dc.creatorTampier de Jong, Lutske
dc.creatorQuintanilla González, María Elena
dc.creatorMardones, Jorge
dc.date.accessioned2019-01-29T14:55:23Z
dc.date.available2019-01-29T14:55:23Z
dc.date.created2019-01-29T14:55:23Z
dc.date.issued1995
dc.identifierAlcohol, Volumen 12, Issue 4, 2018, Pages 341-344
dc.identifier07418329
dc.identifier10.1016/0741-8329(95)00014-I
dc.identifierhttps://repositorio.uchile.cl/handle/2250/161351
dc.description.abstractAminotriazole (AT), a catalase inhibitor, was administered to UChA (low ethanol consumer) and UChB (high ethanol consumer) rats. Ethanol, water, and solid food intake were measured during basic, treatment, and posttreatment periods. The effects of AT on brain catalase activity and acetaldehyde recovered during incubation of brain homogenates with ethanol were also studied in rats of both strains. Results showed that AT decreased voluntary ethanol intake in UChB rats, and also diminished the consumption of food by rats of both strains. No strain difference in brain catalase activity and acetaldehyde recovered during ethanol incubation was observed. The results suggest that AT effect on ethanol consumption is secondary to a reduction in the appetite for calories and not related to its catalase blocking effect. © 1995.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceAlcohol
dc.subject3-Amino-1,2,4-triazole
dc.subjectBrain catalase
dc.subjectEthanol consumption
dc.subjectUChA and UChB rats
dc.titleEffects of aminotriazole on ethanol, water, and food intake and on brain catalase in UChA and UChB rats
dc.typeArtículo de revista


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