Relationship between DNA methylation and cell proliferation in Trypanosoma cruzi

dc.creatorRojas, M.Verónica
dc.creatorGalanti Garrone, Norbel
dc.date.accessioned2019-01-29T14:52:14Z
dc.date.available2019-01-29T14:52:14Z
dc.date.created2019-01-29T14:52:14Z
dc.date.issued1991
dc.identifierFEBS Letters, Volumen 295, Issue 1-3, 2018, Pages 31-34
dc.identifier00145793
dc.identifier10.1016/0014-5793(91)81377-K
dc.identifierhttp://repositorio.uchile.cl/handle/2250/161053
dc.description.abstract5-Azacytidine treatment of T. cruzi epimastigotes in culture induces active cell proliferation. This effect was detected as an increase in the cell number and [3H-methyl]thymidine incorporation into DNA. 5-Azacytidine does not alter other metabolic parameters. We have previously demonstrated that 5-azacytidine induces DNA hypomethylation in T. cruzi. Accordingly, we suggest that this chemical modification may be related to the control of T. cruzi cell division. © 1991.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceFEBS Letters
dc.subject5-Azacytidine
dc.subjectCell proliferation
dc.subjectDNA methylation
dc.subjectTrypanosoma cruzi
dc.titleRelationship between DNA methylation and cell proliferation in Trypanosoma cruzi
dc.typeArtículos de revistas


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