dc.creatorCerda,
dc.creatorBasauri,
dc.date.accessioned2019-01-29T14:20:30Z
dc.date.available2019-01-29T14:20:30Z
dc.date.created2019-01-29T14:20:30Z
dc.date.issued1980
dc.identifierChild's Brain, Volumen 7, Issue 4, 2018, Pages 169-181
dc.identifier03022803
dc.identifierhttps://repositorio.uchile.cl/handle/2250/160419
dc.description.abstractThe cerebrospinal fluid (CSF) protein patterns of 42 children with nontumoral hydrocephalus, 33% with associated congenital malformations (meningocele, myelomeningocele, spina bifida, monoventricular prosencephalon) were determined by isoelectric focusing and polyacrylamide gel electrophoresis. 50% of the patients showed a barrier damage pattern, 19% showed a degenerative pattern, a block pattern or a normal pattern were less frequently found. 14 children presented hydrocephalus associated with other malformations, 44% of these cases showed a degenerative pattern. Combining results from quantitative polyacrylamide gel electrophoresis and qualitative isoelectric focusing, resulted in better characterization of CSF protein abnormalities, the high resolution capacity of these techniques may give a new approach to the evaluation of the blood CSF barrier in the management of hydrocephalus.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceChild's Brain
dc.subjectPediatrics, Perinatology and Child Health
dc.subjectNeuroscience (all)
dc.subjectNeurology (clinical)
dc.titleIsoelectric focusing of cerebrospinal fluid proteins in children with nontumoral hydrocephalus
dc.typeArtículo de revista


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