dc.creator | Cerda, | |
dc.creator | Basauri, | |
dc.date.accessioned | 2019-01-29T14:20:30Z | |
dc.date.available | 2019-01-29T14:20:30Z | |
dc.date.created | 2019-01-29T14:20:30Z | |
dc.date.issued | 1980 | |
dc.identifier | Child's Brain, Volumen 7, Issue 4, 2018, Pages 169-181 | |
dc.identifier | 03022803 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/160419 | |
dc.description.abstract | The cerebrospinal fluid (CSF) protein patterns of 42 children with nontumoral hydrocephalus, 33% with associated congenital malformations (meningocele, myelomeningocele, spina bifida, monoventricular prosencephalon) were determined by isoelectric focusing and polyacrylamide gel electrophoresis. 50% of the patients showed a barrier damage pattern, 19% showed a degenerative pattern, a block pattern or a normal pattern were less frequently found. 14 children presented hydrocephalus associated with other malformations, 44% of these cases showed a degenerative pattern. Combining results from quantitative polyacrylamide gel electrophoresis and qualitative isoelectric focusing, resulted in better characterization of CSF protein abnormalities, the high resolution capacity of these techniques may give a new approach to the evaluation of the blood CSF barrier in the management of hydrocephalus. | |
dc.language | en | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Child's Brain | |
dc.subject | Pediatrics, Perinatology and Child Health | |
dc.subject | Neuroscience (all) | |
dc.subject | Neurology (clinical) | |
dc.title | Isoelectric focusing of cerebrospinal fluid proteins in children with nontumoral hydrocephalus | |
dc.type | Artículo de revista | |