DNA methylation in Trypanosoma cruzi

dc.creatorRojas, M.Véronica
dc.creatorGalanti Garrone, Norbel
dc.date.accessioned2019-01-29T13:56:04Z
dc.date.available2019-01-29T13:56:04Z
dc.date.created2019-01-29T13:56:04Z
dc.date.issued1990
dc.identifierFEBS Letters, Volumen 263, Issue 1, 1990, Pages 113-116
dc.identifier00145793
dc.identifier10.1016/0014-5793(90)80717-W
dc.identifierhttps://repositorio.uchile.cl/handle/2250/160046
dc.description.abstractDNA isolated from the protozoan Trypanosoma cruzi has been found to contain 5-methylcytosine. Analysis of T. cruzi DNA by both HpaII and MspI restriction endonucleases suggests that the sequence -CCGG- is not methylated. Probably T. cruzi DNA also contains N6-methyladenine. This report constitutes the first clear demonstration of the presence of methylated bases in the nuclear DNA from trypanosomes.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceFEBS Letters
dc.subject5-Methylcytosine
dc.subjectBase composition
dc.subjectDNA methylation
dc.subjectTrypanosoma cruzi
dc.titleDNA methylation in Trypanosoma cruzi
dc.typeArtículo de revista


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