dc.creatorArgüello da Silva, Jacqueline
dc.creatorBarría, Claudio Saitz
dc.creatorJullian Matthaei, Carolina
dc.creatorNavarrete, Patricio
dc.creatorNúñez Vergara, Luis
dc.creatorSquella Serrano, Juan
dc.date.accessioned2018-12-20T15:20:42Z
dc.date.available2018-12-20T15:20:42Z
dc.date.created2018-12-20T15:20:42Z
dc.date.issued2005
dc.identifierJournal of the Brazilian Chemical Society, Volumen 16, Issue 1, 2018, Pages 112-115
dc.identifier01035053
dc.identifierhttps://repositorio.uchile.cl/handle/2250/158873
dc.description.abstract1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5′-nitro-2′-furyl)-1,4-dihydropyridine derivatives, which were characterised by 1H-NMR. We have found that carboethoxy groups at the C-3 and C-5 on the 1,4-dihydropyridine ring show a much more complex signal in the 1H NMR spectra, either when C-4 is a pseudo-prochiral or a chiral centre. ©2005 Sociedade Brasileira de Química.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceJournal of the Brazilian Chemical Society
dc.subject1,4-dihydropyridines
dc.subject1H NMR
dc.subjectCarboethoxy group
dc.subjectEnantiotopic methylene hydrogens
dc.subjectNMR
dc.titleUnexpected diastereotopic behaviour in the 1H NMR spectrum of 1,4-dihydropyridine derivatives triggered by chiral and prochiral centres
dc.typeArtículo de revista


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