Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity

dc.creatorPessoa Mahana, Hernán
dc.creatorKosche Cárcamo, Johann
dc.creatorRon Higuera, Nadia
dc.creatorRecabarren Gajardo, Gonzalo
dc.creatorSaitz Barría, Claudio
dc.creatorAraya Maturana, Ramiro
dc.creatorPessoa Mahana, Carlos
dc.date.accessioned2018-12-20T15:10:04Z
dc.date.available2018-12-20T15:10:04Z
dc.date.created2018-12-20T15:10:04Z
dc.date.issued2008
dc.identifierHeterocycles, Volumen 75, Issue 8, 2008, Pages 1913-1929
dc.identifier03855414
dc.identifier10.3987/COM-08-11326
dc.identifierhttps://repositorio.uchile.cl/handle/2250/158129
dc.description.abstractA novel series of 2-benzothiophenealkylpiperazine derivatives 11 (a-d) with potential affinity at 5-HT1A serotonin receptors have been synthesized via solvent-free, microwave-promoted Michael addition of benzo[b]thiophene piperazine derivatives 6(a-c) to substituted benzo[b]thiophen-2-yl propenones 10(b,c).
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceHeterocycles
dc.subjectArylpiperazine
dc.subjectBenzothiophene
dc.subjectDepression
dc.subjectMichael addition
dc.subjectSerotonin
dc.titleSolvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity
dc.typeArtículo de revista


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