Dissolution kinetics evaluation of controlled-release tablets containing propranolol hydrochloride

dc.creatorVelasco-De-Paola, M. V.R.
dc.creatorSantoro, M. I.R.M.
dc.creatorGai, M. N.
dc.date.accessioned2018-12-20T15:04:07Z
dc.date.available2018-12-20T15:04:07Z
dc.date.created2018-12-20T15:04:07Z
dc.date.issued1999
dc.identifierDrug Development and Industrial Pharmacy, Volumen 25, Issue 4, 2018, Pages 535-541
dc.identifier03639045
dc.identifier10.1081/DDC-100102205
dc.identifierhttps://repositorio.uchile.cl/handle/2250/157453
dc.description.abstractIn the present research, controlled-release propranolol hydrochloride tablets were prepared for twice-daily administration, allowing more uniform plasmatic levels of the drug. Pharmaceutical formulations were prepared with hydrophobic Eudragit® RSPO. The physical properties of the tablets were determined. Dissolution tests were performed in capsules containing the raw material using the following dissolution media: (A) distilled water, (B) simulated gastric juice without enzymes, and (C) simulated enteric juice without enzymes. A dissolution test was also performed for simulated samples (tablets) using distilled water as the dissolution medium.
dc.languageen
dc.publisherMarcel Dekker Inc.
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceDrug Development and Industrial Pharmacy
dc.subjectMedicine (all)
dc.subjectPharmacology
dc.subjectDrug Discovery
dc.subjectOrganic Chemistry
dc.titleDissolution kinetics evaluation of controlled-release tablets containing propranolol hydrochloride
dc.typeArtículo de revista


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