| dc.creator | Orellana, Myriam | |
| dc.creator | Rodrigo Salinas, Ramón | |
| dc.creator | Valdés, Elena | |
| dc.date.accessioned | 2018-12-20T14:32:24Z | |
| dc.date.available | 2018-12-20T14:32:24Z | |
| dc.date.created | 2018-12-20T14:32:24Z | |
| dc.date.issued | 1998 | |
| dc.identifier | General Pharmacology, Volumen 31, Issue 5, 2018, Pages 817-820 | |
| dc.identifier | 03063623 | |
| dc.identifier | 10.1016/S0306-3623(98)00054-8 | |
| dc.identifier | http://repositorio.uchile.cl/handle/2250/156377 | |
| dc.description.abstract | 1. Microsomal P450 and peroxisomal fatty acid oxidation activities were studied in liver of rats after long-term ethanol consumption. 2. Ethanol increased the microsomal lauric acid ω-hydroxylation and the aminopyrine N-demethylation catalyzed by cytochrome P450. 3. Ethanol increased peroxisomal β-oxidation of palmitoyl CoA and catalase activity in liver. 4. Both microsomal and peroxisomal activities behaved in a coordinate way in the liver of rats with long-term ethanol consumption. 5. These results would support a role of microsomal ω-hydroxylation and peroxisomal β-oxidation of fatty acids in an extramitochondrial pathway of lipid oxidation in the liver. Copyright (C) 1998 Elsevier Science Inc. | |
| dc.language | en | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| dc.source | General Pharmacology | |
| dc.subject | Aminopyrine | |
| dc.subject | Catalase | |
| dc.subject | Cytochrome P450 | |
| dc.subject | Ethanol | |
| dc.subject | Lauric acid | |
| dc.subject | Peroxisomal fatty acid oxidation | |
| dc.title | Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption | |
| dc.type | Artículos de revistas | |
