| dc.creator | Orellana, Myriam | |
| dc.creator | Valdés, Elena | |
| dc.creator | Del Villar, Eugenia | |
| dc.date.accessioned | 2018-12-20T14:32:18Z | |
| dc.date.available | 2018-12-20T14:32:18Z | |
| dc.date.created | 2018-12-20T14:32:18Z | |
| dc.date.issued | 1997 | |
| dc.identifier | General Pharmacology, Volumen 28, Issue 3, 2018, Pages 361-364 | |
| dc.identifier | 03063623 | |
| dc.identifier | 10.1016/S0306-3623(96)00231-5 | |
| dc.identifier | https://repositorio.uchile.cl/handle/2250/156340 | |
| dc.description.abstract | Microsomal lauric acid hydroxylation and fatty acid peroxisomal β-oxidation were studied in hepatic subcellulant preparations from streptozotocin-induced diabetic and diabetic insulin-treated rats. The liver microsomes of the streptozotocin diabetic rats displayed a similar activity to hydroxylate lauric acid as the control microsomes. Diabetic insulin-treated rats showed lower (ω1) and ω-lauric acid hydroxylase activities than diabetic and control rats. Streptozotocin-induced diabetes and diabetic insulin-treated rats exhibited no significant changes on peroxisomal palmitoyl CoA β-oxidation compared to the control rats. Both microsomal and peroxisomal fatty acid oxidation responded in a similar way in this model of experimental diabetes. | |
| dc.language | en | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| dc.source | General Pharmacology | |
| dc.subject | lauric acid | |
| dc.subject | liver cytochrome P-450 | |
| dc.subject | peroxisomal fatty acid β-oxidation | |
| dc.subject | streptozotocin-diabetic | |
| dc.title | Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver | |
| dc.type | Artículo de revista | |
