Artículos de revistas
Totally Organic Redox-Active pH-Sensitive Nanoparticles Stabilized by Amphiphilic Aromatic Polyketones
Fecha
2018Registro en:
Journal of Physical Chemistry B, Volumen 122, Issue 5, 2018, Pages 1747-1755
15205207
15206106
10.1021/acs.jpcb.7b11254
Autor
Araya Hermosilla, Esteban
Catalán-Toledo, José
Muñoz-Suescun, Fabián
Oyarzún Ampuero, Felipe
Raffa, Patrizio
Polgar, Lorenzo Massimo
Picchioni, Francesco
Moreno-Villoslada, Ignacio
Institución
Resumen
© 2018 American Chemical Society. Amphiphilic aromatic polymers have been synthesized by grafting aliphatic polyketones with 4-(aminomethyl)benzoic acid at different molar ratios via the Paal-Knorr reaction. The resulting polymers, showing diketone conversion degree of 16%, 37%, 53%, and 69%, have been complexed with the redox-active 2,3,5-triphenyl-2H-tetrazolium chloride, a precursor molecule with which aromatic-aromatic interactions are held. Upon addition of ascorbic acid to the complexes, in situ reduction of the tetrazolium salt produced 1,3,5-triphenylformazan nanoparticles stabilized by the amphiphilic polymers. The stabilized nanoparticles display highly negative zeta potential [-(35-70) mV] and hydrodynamic diameters in the submicron range (100-400 nm). Nonaromatic polyelectrolytes or hydrophilic aromatic copolymers showing low linear aromatic density and high linear charge density such as acrylate/maleate and sulfonate/maleate-containing polymers were unable to stabilize for