A DFT analysis of the strain-induced regioselective[2+2]cycloaddition of benzyne possessing fused four-membered ring

dc.creatorDomingo, L. R.
dc.creatorPérez, Patricia
dc.creatorContreras Ramos, Renato
dc.date.accessioned2018-12-20T14:11:10Z
dc.date.available2018-12-20T14:11:10Z
dc.date.created2018-12-20T14:11:10Z
dc.date.issued2005
dc.identifierLetters in Organic Chemistry, Volumen 2, Issue 1, 2018, Pages 68-73
dc.identifier15701786
dc.identifier10.2174/1570178053399958
dc.identifierhttps://repositorio.uchile.cl/handle/2250/154489
dc.description.abstractThe regioselective [2+2] cycloaddition of a substituted benzyne possessing a fused four-membered ring to a ketene acetal has been theoretically studied. This cycloaddition presents a two-step mechanism that is initiated by the nucleophilic attack to the benzyne to give a zwitterionic intermediate. The analysis performed on the basis of the global and local electrophilicity of reagents correctly explain the observed reactivity and regioselectivity in this system. © 2005 Bentham Science Publishers Ltd.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceLetters in Organic Chemistry
dc.subject[2+2] Cyloadditions
dc.subjectAngle strain
dc.subjectBenzyne
dc.subjectDFT calculations
dc.subjectRegioselectivity
dc.titleA DFT analysis of the strain-induced regioselective[2+2]cycloaddition of benzyne possessing fused four-membered ring
dc.typeArtículo de revista


Este ítem pertenece a la siguiente institución