Chile | Artículo de revista

Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments

dc.creatorValdés Camus, Karina
dc.creatorMorales, Javier
dc.creatorRodríguez, Lennin
dc.creatorGünther Sapunar, Germán
dc.date.accessioned2018-03-06T14:41:41Z
dc.date.available2018-03-06T14:41:41Z
dc.date.created2018-03-06T14:41:41Z
dc.date.issued2016-12
dc.identifierNanomedicine Volume: 11 Issue: 23
dc.identifier1748-6963
dc.identifier10.2217/nnm-2016-0251
dc.identifierhttps://repositorio.uchile.cl/handle/2250/146702
dc.description.abstractUrsolic, oleanolic and betulinic acids are representative pentacyclic triterpenoids found in various plants and fruits. Despite having marked antitumor potentials, the very poor water solubility of these triterpenes hinders treatment development. Nanotechnology can enhance solubility, stability, bioavailability and phytochemical delivery, improving the therapeutic efficiency of triterpenes. This review focuses on the formulation, characterization and in vitro/in vivo evaluation of several delivery nanosystems used to enhance the physicochemical properties of ursolic, oleanolic and betulinic acids.
dc.languageen
dc.publisherFuture Medicine Ltd
dc.sourceNanomedicine
dc.subjectursolic acid
dc.subjectoleanolic acid
dc.subjectnanotechnology
dc.subjectnanosystems
dc.subjectnanoparticles
dc.subjectnanoemulsion
dc.subjectnanocarriers
dc.subjectliposomes
dc.subjectbetulinic acid
dc.subjectantitumoral
dc.titlePotential use of nanocarriers with pentacyclic triterpenes in cancer treatments
dc.typeArtículo de revista


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