dc.creator | Duffau, Boris | |
dc.creator | Camargo Grandón, Rodrigo | |
dc.creator | Kogan Bocian, Marcelo | |
dc.creator | Fuentes Pérez, Edwar | |
dc.creator | Cassels Niven, Bruce | |
dc.date.accessioned | 2017-12-21T13:58:54Z | |
dc.date.available | 2017-12-21T13:58:54Z | |
dc.date.created | 2017-12-21T13:58:54Z | |
dc.date.issued | 2016 | |
dc.identifier | Journal of Chromatographic Science, 2016, Vol. 54, No. 7, 1153–1158 | |
dc.identifier | 0021-9665 | |
dc.identifier | 10.1093/chromsci/bmw095 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/146231 | |
dc.description.abstract | Use of unauthorized synthetic drugs is a serious, forensic, regulatory and public health issue. In this scenario, consumption of drug-impregnated blotters is very frequent. For decades, blotters have been generally impregnated with the potent hallucinogen known as lysergic acid diethylamide (LSD); however, since 2013 blotter stamps with N-2 methoxybenzyl-substituted phenylethylamine hallucinogen designated as "NBOMes" have been seized in Chile. To address this issue with readily accessible laboratory equipment, we have developed and validated a new HPTLC method for the identification and quantitation of 25-C-NBOMe in seized blotters and its confirmation by GC-MS. The proposed method was validated according to SWGTOX recommendations and is suitable for routine analysis of seized blotters containing 25-C-NBOMe. With the validated method, we analyzed 15 real samples, in all cases finding 25-C-NBOMe in a wide dosage range (701.0-1943.5 mu g per blotter). In this situation, we can assume that NBOMes are replacing LSD as the main hallucinogenic drug consumed in blotters in Chile | |
dc.language | en | |
dc.publisher | Oxford University Press | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Journal of Chromatographic Science | |
dc.subject | Validation | |
dc.subject | Drug | |
dc.subject | Uncertainty | |
dc.subject | Agonists | |
dc.subject | Series | |
dc.subject | Guide | |
dc.title | Analysis of 25 C NBOMe in Seized Blotters by HPTLC and GC–MS | |
dc.type | Artículo de revista | |