dc.creator | iordano, Ady | |
dc.creator | Vásquez, José | |
dc.creator | Retamal, Mauricio | |
dc.creator | Ascar Estay, María Loreto | |
dc.date.accessioned | 2017-11-28T16:01:08Z | |
dc.date.available | 2017-11-28T16:01:08Z | |
dc.date.created | 2017-11-28T16:01:08Z | |
dc.date.issued | 2016 | |
dc.identifier | J. Braz. Chem. Soc., Vol. 27, No. 10, 1744-1749, 2016. | |
dc.identifier | 0103-5053 | |
dc.identifier | 10.5935/0103-5053.20160055 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/145873 | |
dc.description.abstract | The use of thin-film microextraction for the extraction of selected pharmaceutical compounds followed by gas chromatography-mass spectrometry detection was evaluated. A segment of polysiloxanes polymer sheet was used as low cost, single use, disposable extraction phase, while Milli-Q water spiked at 20 mu g L-1 with the analytes was used for the optimization assays. The controlling parameters for the extraction were optimized via experimental design and it was found that an extraction time of 3 h using a sample volume of 1000 mL at pH 4 with the addition of 20% methanol and 20% sodium chloride provided the greatest extraction efficiency. Recoveries between 67.1 and 85.0% were achieved, with a repeteability lower than 20% (expressed as coefficient of variation) and limit of detection ranged from 0.41 and 0.92 mu g L-1. The proposed method show similar analytical performance when compared to the determination of the analytes using stir bar sorptive extraction | |
dc.language | en | |
dc.publisher | Sociedad Brasileira de Quimica | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Journal of the Brazilian Chemical Society | |
dc.subject | Thin-film extraction | |
dc.subject | Beta-estradiol | |
dc.subject | Carbamazepine | |
dc.subject | Ibuprofen | |
dc.title | Ibuprofen, Carbamazepine and β-Estradiol Determination Using Thin-Film Microextraction and Gas Chromatography-Mass Spectrometry | |
dc.type | Artículo de revista | |