Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

dc.creatorLord, Phillip
dc.creatorSpiering, Rachel
dc.creatorAguillón Gutiérrez, Juan Carlos
dc.creatorAnderson, Amy E.
dc.creatorAppel, Silke
dc.creatorBenítez Ribas, Daniel
dc.creatorTen Brinke, Anja
dc.creatorBroere, Femke
dc.creatorCools, Nathalie
dc.creatorCuturi, María Cristina
dc.creatorDiboll, Julie
dc.creatorGeissler, Edward K.
dc.creatorGiannoukakis, Nick
dc.creatorGregori, Silvia
dc.creatorvan Ham, S. Marieke
dc.creatorLattimer, Staci
dc.creatorMarshall, Lindsay
dc.creatorHarry, Rachel A.
dc.creatorHutchinson, James A.
dc.creatorIsaacs, John D.
dc.creatorJoosten, Irma
dc.creatorvan Kooten, Cees
dc.creatorLópez Díaz de Cerio, Ascension
dc.creatorNikolic, Tatjana
dc.creatorOral, Haluk Barbaros
dc.creatorSofronic Milosavljevic, Ljiljana
dc.creatorRitter, Thomas
dc.creatorRiquelme, Paloma
dc.creatorThomson, Angus W.
dc.creatorTrucco, Massimo
dc.creatorVives Pi, Marta
dc.creatorMartínez Cáceres, Eva M.
dc.creatorHilkens, Catharien M.
dc.date.accessioned2017-03-01T20:45:39Z
dc.date.accessioned2019-04-26T01:09:48Z
dc.date.available2017-03-01T20:45:39Z
dc.date.available2019-04-26T01:09:48Z
dc.date.created2017-03-01T20:45:39Z
dc.date.issued2016
dc.identifierPEERJ. Volumen: 4 Número de artículo: e2300
dc.identifier10.7717/peerj.2300
dc.identifierhttp://repositorio.uchile.cl/handle/2250/142899
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/2446987
dc.description.abstractCellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies for generating tolAPC vary greatly between different laboratories, making it difficult to compare data from different studies; thus constituting a major hurdle for the development of standardised tolAPC therapeutic products. Here we describe an initiative by members of the tolAPC field to generate a minimum information model for tolAPC (MITAP), providing a reporting framework that will make differences and similarities between tolAPC products transparent. In this way, MITAP constitutes a first but important step towards the production of standardised and reproducible tolAPC for clinical application.
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourcePEERJ
dc.subjectReporting guidelines
dc.subjectRegulatory macrophages
dc.subjectTolerogenic dendritic cells
dc.subjectTransplantation
dc.subjectAutoimmune disease
dc.subjectAntigen-presenting cells
dc.subjectMinimum information model
dc.subjectCell therapy
dc.titleMinimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies
dc.typeArtículos de revistas


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