dc.creator | Jirón Aliste, Marcela | |
dc.creator | Pate, Virginia | |
dc.creator | Hanson, Laura C. | |
dc.creator | Lund, Jennifer L. | |
dc.creator | Jonsson Funk, Michele | |
dc.creator | Stuermer, Til | |
dc.date.accessioned | 2016-10-25T20:10:24Z | |
dc.date.available | 2016-10-25T20:10:24Z | |
dc.date.created | 2016-10-25T20:10:24Z | |
dc.date.issued | 2016 | |
dc.identifier | JAGS 64:788–797, 2016 | |
dc.identifier | 10.1111/jgs.14077 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/140965 | |
dc.description.abstract | ObjectivesTo estimate the prevalence and determinants of the use of potentially inappropriate medications (PIMs) in older U.S. adults using the 2012 Beers criteria.
DesignRetrospective cohort study in a random national sample of Medicare beneficiaries.
SettingFee-for-service Medicare beneficiaries from 2007 to 2012.
ParticipantsU.S. population aged 65 and older with Parts A, B, and D enrollment in at least 1month during a calendar year (N=38,250 individuals; 1,308,116 observations).
MeasurementsThe 2012 Beers criteria were used to estimate the prevalence of the use of PIMs in each calendar month and over a 12-month period using data on diagnoses or conditions present in the previous 12months. Generalized estimating equations were used to account for the dependence of multiple monthly observations of a single person when estimating 95% confidence intervals (CIs), and logistic regression was used to identify independent determinants of PIM use.
ResultsThe point prevalence of the use of PIMs decreased from 37.6% (95% CI=37.0-38.1) in 2007 to 34.2% (95% CI=33.6-34.7) in 2012, with a statistically significant 2% (95% CI=1-3%) decline per year assuming a linear trend. The 1-year period prevalence declined from 64.9% in 2007 to 56.6% in 2012. The strongest predictor of PIM use was the number of drugs dispensed. Individuals aged 70 and older and those seen by a geriatrician were less likely to receive a PIM.
ConclusionFrom 2007 to 2012, the prevalence of PIM use in older U.S. adults decreased according to the 2012 Beers criteria, although it remains high, still affecting one-third each month and more than half over 12months. The number of dispensed prescriptions could be used to target future interventions. | |
dc.language | en | |
dc.publisher | Wiley-Blackwell | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Journal of the American Geriatrics Society | |
dc.subject | Potentially inappropriate medications | |
dc.subject | Beers criteria | |
dc.subject | Older adults | |
dc.subject | Database study | |
dc.subject | Pharmacoepidemiology | |
dc.subject | Medicare | |
dc.title | Trends in Prevalence and Determinants of Potentially Inappropriate Prescribing in the United States: 2007 to 2012 | |
dc.type | Artículo de revista | |