| dc.description.abstract | Cypermethrin is a synthetic pyrethroid widely used as an
agropesticide. The aim of this study was to determine the effect
of cypermethrin on reproductive patterns of the planarian
Dugesia gonocephala, a bioindicator species from Guacollo
River, in the Chilean Altiplano, an ecosystem that is free of
regular environmental pollutants. Specimens were subjected
to doses of 1.455, 0.1455, 0.01455, 0.001455, 0.0001455 and
0.00001455mg·ml-1 cypermethrin (1/10, 1/100, 1/1000, 1/10000
and 1/1000000 LD50, respectively). Planarians incubated in water
from the same river were the control. The results showed
that cypermethrin modified the morphology of the seminiferous
tubules significantly increasing the area and perimeter of
the tubules, also causing cellular changes, with a significant
increase in (CD133+) stem cells. Is concluded that D. gonocephala
is an excellent biomarker of environmental pollutants
in aquatic ecosystems, and cypermethrin alters the architecture
and cell proliferation of germ cells of the seminiferous tubules,
possibly as a result of oxidative stress. | |
