dc.creatorGaspers, Serge
dc.creatorLiedloff, Mathieu
dc.creatorStein, Maya
dc.creatorSuchane, Karol
dc.date.accessioned2015-08-18T12:28:09Z
dc.date.available2015-08-18T12:28:09Z
dc.date.created2015-08-18T12:28:09Z
dc.date.issued2015
dc.identifierDiscrete Applied Mathematics 180 (2015) 89–100
dc.identifierDOI: 10.1016/j.dam.2014.08.005
dc.identifierhttps://repositorio.uchile.cl/handle/2250/132810
dc.description.abstractGiven a vertex-weighted tree T , the split of an edge e in T is the minimum over the weights of the two trees obtained by removing e from T , where the weight of a tree is the sum of weights of its vertices. Given a set of weighted vertices V and a multiset of integers S, we consider the problem of constructing a tree on V whose splits correspond to S. The problem is known to be NP-complete, even when all vertices have unit weight and the maximum vertex degree of T is required to be at most 4. We show that • the problem is strongly NP-complete when T is required to be a path, • the problem is NP-complete when all vertices have unit weight and the maximum degree of T is required to be at most 3, and • it remains NP-complete when all vertices have unit weight and T is required to be a caterpillar with unbounded hair length and maximum degree at most 3. We also design polynomial time algorithms for • the variant where T is required to be a path and the number of distinct vertex weights is constant, and • the variant where all vertices have unit weight and T has a constant number of leaves. The latter algorithm is not only polynomial when the number of leaves, k, is a constant, but also is a fixed-parameter algorithm for parameter k. Finally, we shortly discuss the problem when the vertex weights are not given but can be freely chosen by an algorithm. The considered problem is related to building libraries of chemical compounds used for drug design and discovery. In these inverse problems, the goal is to generate chemical compounds having desired structural properties, as there is a strong relation between structural invariants of the particles, such as the Wiener index and, less directly, the problem under consideration here, and physico-chemical properties of the substance.
dc.languageen_US
dc.publisherElsevier
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile
dc.subjectReconstruction of trees
dc.subjectComputational complexity
dc.subjectComputational chemistry
dc.titleComplexity of splits reconstruction for low-degree trees
dc.typeArtículo de revista


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