| dc.creator | Smith, P. C. | |
| dc.creator | Guerrero, J. | |
| dc.creator | Tobar, N. | |
| dc.creator | Cáceres, M. | |
| dc.creator | González Burgos, María Julieta | |
| dc.creator | Martínez Winkler, Jorge | |
| dc.date.accessioned | 2014-01-10T14:17:27Z | |
| dc.date.available | 2014-01-10T14:17:27Z | |
| dc.date.created | 2014-01-10T14:17:27Z | |
| dc.date.issued | 2007-12-11 | |
| dc.identifier | J Periodont Res 2009; 44: 73–80 | |
| dc.identifier | doi:10.1111/j.1600-0765.2007.01081.x | |
| dc.identifier | https://repositorio.uchile.cl/handle/2250/123508 | |
| dc.description.abstract | Membrane type 1-matrix metalloproteinase (MT1-
MMP) is a collagenolytic enzyme involved in connective tissue remodeling. In
periodontal tissues, either cytokines or growth factors regulate the production of
proteolytic enzymes. Mice deficient in epidermal growth factor receptor (EGFR)
show a reduced expression of MT1-MMP, suggesting that this receptor may play
an important role in MT1-MMP production. The present study evaluated the role
of the inflammatory cytokine tumor necrosis factor-a (TNF-a) and EGFR in the
production of MT1-MMP in gingival fibroblasts. | |
| dc.language | en | |
| dc.publisher | Blackwell Munksgaard | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| dc.subject | tumor necrosis factor-a; epidermal growth factor receptor; membrane type 1-matrix metalloproteinase; fibroblast | |
| dc.title | Tumor necrosis factor-astimulated membrane type 1-matrix metalloproteinase production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts | |
| dc.type | Artículo de revista | |
