Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity

dc.creatorPessoa Mahana, Hernán
dc.creatorAcevedo Ramos, Armando Rodrigo
dc.creatorAraya Maturana, Ramiro
dc.creatorSaitz Barría, Claudio
dc.creatorPessoa, D.
dc.date.accessioned2010-06-01T19:58:12Z
dc.date.available2010-06-01T19:58:12Z
dc.date.created2010-06-01T19:58:12Z
dc.date.issued2007
dc.identifierSYNTHETIC COMMUNICATIONS 37(19-21): 3559-3567
dc.identifier0039-7911
dc.identifierhttps://repositorio.uchile.cl/handle/2250/120949
dc.description.abstractNew benzothiophene arylpiperazine derivatives 8 (a-f) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by treating N-[2-(chloromethyl)phenyl]-4,7-dimethoxybenzo[b]thiophene-2-carboxamide (7) with a series of substituted 4-arylpiperazines.
dc.languageen
dc.publisherTAYLOR & FRANCIS INC
dc.subjectArylpiperazines
dc.titleSynthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity
dc.typeArtículo de revista


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