Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action

dc.creatorPessoa Mahana, Hernán
dc.creatorRecabarren Gajardo, Gonzalo Iván
dc.creatorAraya Maturana, Ramiro
dc.creatorPessoa, D.
dc.creatorKosche Cárcamo, Johann Albert
dc.date.accessioned2010-06-01T19:51:37Z
dc.date.available2010-06-01T19:51:37Z
dc.date.created2010-06-01T19:51:37Z
dc.date.issued2004-07
dc.identifierSYNTHETIC COMMUNICATIONS 34(14): 2513-2521
dc.identifier0039-7911
dc.identifierhttps://repositorio.uchile.cl/handle/2250/120948
dc.description.abstractWe report here the synthesis of substituted 4-chloro-N-[3-oxo-3-(4-aryl-1-piperazinyl)-propyl] benzamides (5-9), as potential new antidepressants, incorporating in a single molecule structural moieties related to a dual pharmacological profile: MAO-A inhibitor and 5-HT1A receptor affinity.
dc.languageen
dc.publisherMARCEL DEKKER INC
dc.subjectArylpiperazine
dc.titleSynthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action
dc.typeArtículo de revista


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