Prevalencia y factores asociados a la no adherencia en el tratamiento farmacológico de mantenimiento en adultos con trastorno afectivo bipolar

Abstract

The prevalence of nonadherence in the maintenance treatment of Bipolar Affective Disorder is in the ranges of 20% and 60%, speaking various patient-related factors, disease, treatment, and the relationship with the therapist, associated with increased morbidity, mortality and risk of hospital readmissions.This study aimed to determine the prevalence and factors associated with nonadherence in maintenance treatment of adult patients diagnosed with bipolar affective disorder. Methods: Cross sectional study included 124 patients that visited the months of November and December, was applied structutured questionnaire that include variables associated factors demographics, related to the patient, with illness, treatment, therapeutic relationship and health system, related to the family; the Global Impression Scale Modified for Bipolar Disorder (CGI - BPM-M) and family apgar Results: The prevalence of non-adherence to maintenance drug treatment was 29.8%. Since this is greater for women (64.9%) than men (35.1%), although this difference was not statistically significant (p = 0.17). The statistically significant factors were related to increased severity of disease OR 1.9, history of nonadherence (38% P = 0,001), negative perception of the therapist, the less insight (87% RP4.65), greater stigma (50% RP 6.2) , have no family member to remember taking the drug (73%). Conclusions: The prevalence ranged from studies by Scott, Vieta et al, associated factors such as stigma, history of non-compliance, no family support, a poor insight into the habit of smoking can be identified from the approach Patient and modified to improve adherence