Neurocirugia radioguiada en los tumores cerebrales de alto grado, experiencia INC

Abstract

Radioguided surgery is a branch of nuclear medicine which marks the tumor tissue with a radiotracer (MIBI) and using one gammacamera or gammaprobe to differentiate from healthy brain tissue in vivo in the operating room. This technique has been successfully implemented in CNS tumors (9-14) (high grade gliomas, metastases, meningiomas). CNS tumors represent 1% of all tumors but they are the third leading cause of cancer mortality in the world. There is a better prognosis for patients with more extensive resection. Objectives: To evaluate the feasibility of the technique and optimize processes in the INC in order to develop a line of research protocol in this matter. Materials and methods: Patients diagnosed with supratentorial brain tumor. Brain SPECT was performed to confirm MIBI uptake of the radiotracer. In patients who tested positive radioguided surgery was scheduled with portable gamacámara Sentinel Results: In 5 patients with supratentorial tumors SPECT was performed with MIBI: 3 with SPECT positive were scheduled for surgery radioguided and the remaining 2 with conventional surgery. Two positive cases were for high-grade tumor and a case of abscessed tumor. At surgery, complete resection is achieved radioguided tumor by intraoperative gamacámara image