Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales

Abstract

Coronary artery disease (CAD) is still the first cause of morbidity and mortality in the general population. CAD has genetic, social, cultural, environmental and race backgroundsbesides the traditional major risks factors. It is unknown the impact of race in CAD´s severity within patients from Netherland Antilles, frequently referred to our service. Purpose:To compare the severity and extension of multivessel coronary artery disease by SYNTAX score between patients from Netherland Antilles vs Colombian patients after matching by Framingham Score Materials and Methods: We carried out a transversal cross sectional study by comparing patients from the Netherland Antilles vs Colombian patients after matching by Framingham Score in four categories (low risk, intermediate risk, high risk and very high risk). The patients correspond to those having multivessel coronary artery disease diagnosed by coronary angiography between January 2009 to June 2011. Results: 115 Colombian patients and 115 patients coming from the Netherland Antilles were included in this study, in a 3:1 ratio between females and males.. The proportion of patients belonging to several groups of risk where as follows: 2.5% low risk, 15% intermediate risk, 19.3% high risk, and 63.4% very high risk. The Syntax score for coronary artery disease was significantly higher among Caribbean from the Netherland Antilles (22.2+/-10.5) than among Colombians (14.3+/-7.4) p: 0.002. Conclusions: Patients coming from the Netherland Antilles had a higher severity index for coronary disease measured by angiography, after controlling for recognized risk factors. These findings support the notion that coronary disease is influenced by race, and genetic backgrounds. This finding is important for policies making in our service, a referral place for international patients.