masterThesis
Factores asociados en el desarrollo de cáncer de senos nasales y paranasales en trabajadores de la industria de la madera : revisión sistemática
Fecha
2018Autor
Blandón Castaño, Yury Paola
Gutiérrez Moreno, Karen Lorena
Institución
Resumen
Introduction: The first evidence of a possible association between nasal cancer and exposure to wood dust was published in England in 1960. Malignant tumors of the nose and sinonasal cavities are relatively infrequent, representing between 0. 2% and 0. 8% of the malignant tumors of the organism. Objective: To establish the factors associated in the development of sinus and paranasal cancer in workers of the wood industry. Materials and methods: Through a systematic review of the literature in the PubMed, Scopus, SciELO and Cochrane databases, articles were selected between 1968 and 2018 in English and Spanish using the MeSH terms or keywords: occupational , factors, cancer, sinonasal, wood and the Boolean operators AND and OR. Results: Exposure to wood dust was associated with an increased risk in men for the development of adenocarcinoma in cabinetmakers (OR = 35. 4, 95% CI = 18. 1-69. 3) and carpenters (OR = 25. 2, 95% CI = 14. 6 -43. 6), in relation to women, an increased risk of squamous cell carcinoma (SCC) was found (OR = 9. 5, 95% CI = 1. 7-54. 1) and it was observed that the development of adenocarcinoma is mainly associated with exposure to hard wood (OR: 33. 8 95% CI: 3. 22-351 p: 0. 003. ) The average age at diagnosis was 62 years. Conclusion: Among the risk factors associated with the development of nasal and paranasal sinus cancer in the working population, exposure to hardwood dust, long-term exposure time and sex were found, being more predominant in men apparently related to work activity.