dc.contributorFernández Sarmiento, Jaime
dc.creatorOrozco Marun, Rafael Jose
dc.creatorFernández Sarmiento, Jaime
dc.creatorMorón Duarte, Lina Sofía
dc.date.accessioned2014-08-12T13:19:17Z
dc.date.available2014-08-12T13:19:17Z
dc.date.created2014-08-12T13:19:17Z
dc.date.issued2014
dc.identifierhttp://repository.urosario.edu.co/handle/10336/8784
dc.identifierhttps://doi.org/10.48713/10336_8784
dc.description.abstractIntroduction: Sepsis is a major cause of morbidity and mortality in the pediatric population worldwide. It is widely known that low cardiac output is one of the main factors associated with mortality in pediatric sepsis. It has been suggested venoarterial pCO2 difference as predictor of myocardial function in patients with sepsis, however, to date no studies in children have been done to asses it. Objective: The aim of this study was to determine the predictive capacity and operational characteristics of venoarterial pCO2 difference as predictor of myocardial dysfunction in pediatric patients with severe sepsis and septic shock. Methods: In order to achieve the objectives of the study, it was performed a prospective study of diagnostic tests. Echocardiogram and venoarterial pCO2 difference were done to each patient, then the operating characteristics of the venoarterial difference of pCO2 were calculated, to determine its usefulness. Results: 71 patients were included. The median venoarterial pCO2 difference was not significantly higher in patients who had cardiac dysfunction on echocardiography compared with those with no dysfunction. A statistically significant relationship of values from 1. 5 to 2. 1 mmHg, as a negative predictor of myocardial dysfunction with a sensitivity of 100% and a specificity of 88% was found. Conclusions: The difference venoarterial pCO2 is not yet a good predictor of myocardial dysfunction in pediatric patients with severe sepsis and septic shock, even when other biomarkers are within normal limits. More clinical essays are requerided
dc.languagespa
dc.publisherUniversidad del Rosario
dc.publisherEspecialización en Cuidado Intensivo Pediátrico
dc.publisherFacultad de medicina
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAbierto (Texto Completo)
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 Colombia
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dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectSepsis
dc.subjectCardiomiopatía
dc.subjectDiferencia venoarterial de pCO2
dc.subjectDisfunción miocárdica
dc.titleDiferencia venoarterial de Pco2 como predictor de disfunción miocárdica en niños con sepsis severa y choque séptico.
dc.typemasterThesis


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