Supervivencia en una cohorte de pacientes con adenocarcinoma gástrico resecable, Bogotá, 2005-2018

Abstract

Introduction: Gastric cancer is the fifth most common malignancy in the world, and the third cause of cancer death in the world. It is important to know in Colombia the global survival and the disease-free survival at 5 years, as well as prognostic factors. Methods: We reviewed 106 medical records of a cancer center in Bogotá, Colombia from January 2005 to June 2018. We performed a survival analysis using the Kaplan Meier method, Log-rank test and COX regression. Results: The median follow-up was 21 months, the majority of patients were males (53.7%), have early diagnosis in 63.2% (stages 0, I and II), median age of diagnosis of 57.8 years, have none lymph node involved (44.3%), intestinal histological type (45.3%) and poorly differentiated (57.5%). Disease-free survival at 1, 3 and 5 years was 84%, 53% and 46.3%; and overall survival was 94.1%, 82% and 69.4%. The number of lymph nodes involved in the diagnosis of disease-free survival was found as a prognostic factor (1-2 lymph nodes: HR 6.46 IC95% 1.16-35.92, 3-6 nodes: HR 4.44 IC95% 1.25-15.77, and ≥7 nodes: HR 10.84 IC95% 3.57-32.9) and for overall survival (≥7 nodes: HR 6.56 IC95% 1.69-25.37). Conclusion: The overall survival and disease free survival was greater than the described in the literature, finding as a risk factor for disease-free survival and overall survival, the number of lymph nodes involved at diagnosis.