dc.contributorHernández Leiva, Edgar
dc.creatorPeña Peña, Adwar
dc.creatorOrtiz García, César Augusto
dc.date.accessioned2017-02-07T12:28:47Z
dc.date.available2017-02-07T12:28:47Z
dc.date.created2017-02-07T12:28:47Z
dc.date.issued2017
dc.identifierhttp://repository.urosario.edu.co/handle/10336/12893
dc.identifierhttps://doi.org/10.48713/10336_12893
dc.description.abstractIntroduction: Acute Kidney Injury (AKI) is one of the major complications of cardiacsurgery. AKI has been shown as an independent risk factor for both, early and latepostoperative death in this population. The knowledge of the factors that lead to acute renal injury would help to reduce this complication. Methods: Case control study. The objective of this study was to evaluate the factorsassociated with acute renal injury in patients undergoing cardiac surgery, with the hypothesis that Brain Natriuretic Peptide (BNP), low hemoglobin, and an elevated EuroSCORE and serum creatinine, are associated with the occurrence of AKI in the postoperative period. Results: A total of 491 patients were analyzed, 141 women (28. 72%), 35 of them (7. 13%)met criteria for AKI in the postoperative period. Patients with AKI had a higher meancreatinine level in the preoperative period (p< 0. 001) and had a greater EuroSCORE(p< 0. 001). Univariate analysis showed that preoperative BNP was higher (p< 0. 001) andhematocrit was lower in the AKI group (p < 0. 004). Factors associated with LRA were: BNP pμ / ml> 300 OR 3. 9 IC95% (1. 6-9. 5), presence of previous arrhythmia OR 5. 4 95% CI (2. 2-13. 5), EuroSCORE standard OR 1. 2 IC95% (1. 0-1. 3), surgery Valvular OR 2. 7 IC95% (0. 8-7. 6). Conclusion: Elevated preoperative BNP, the presence of previous arrhythmia, a valvularsurgery and EuroSCORE are associated with increased risk for impaired renal function and requirement for renal replacement therapy in postoperative cardiovascular surgery patients.
dc.languagespa
dc.publisherUniversidad del Rosario
dc.publisherEspecialización en Medicina Interna
dc.publisherFacultad de Medicina
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAbierto (Texto completo)
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rightsEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.
dc.sourceLeiva EH, Verano RD, Bucheli FR, Restre- DI, García CO, Pablo J, et al. Can the Predictive Power of EuroSCORE Be Improved by Adding Preoperative Hemoglobin or B-type Natriuretic Peptide ( BNP ) Values ? J Hear Surg Treat. 2014;1(1):1–15.
dc.sourceKarkouti K, Wijeysundera DN, Yau TM, Callum JL, Cheng DC, Crowther M, et al. Acute kidney injury after cardiac surgery. Focus on modifiable risk factors. Circulation. 2009;119(4):495–502.
dc.sourceO’Neal JB, Shaw AD, Billings FT. Acute kidney injury following cardiac surgery: current understanding and future directions. Crit care [Internet]. Critical Care; 2016;20(1):187.
dc.sourcePalomba H, De Castro I, Neto A, Lage S, Yu L. Acute kidney injury prediction following elective cardiac surgery: AKICS Score. Kidney Int. 2007;72:624–31.
dc.sourceKowalik MM, Lango R, Klajbor K, Musiał-Świa̧tkiewicz V, Koaczkowska M, Pawlaczyk R, et al. Incidence- and mortality-related risk factors of acute kidney injury requiring hemofiltration treatment in patients undergoing cardiac surgery: A single-center 6-year experience. J Cardiothorac Vasc Anesth. 2011;25(4):619–24.
dc.sourceKolli H, Rajagopalam S, Patel N, Ranjan R, Venuto R, Lohr J, et al. Mild acute kidney injury is associated with increased mortality after cardiac surgery in patients with eGFR < 60 mL/min/1.73 m(2). Ren Fail [Internet]. 2010;32(9):1066–72.
dc.sourceMachado MN, Nakazone MA, Maia LN. Acute kidney injury based on KDIGO (Kidney Disease Improving Global Outcomes) criteria in patients with elevated baseline serum creatinine undergoing cardiac surgery. Rev Bras Cir Cardiovasc [Internet]. 2014;29(3):299–307.
dc.sourcede Moura EB, Bernardes Neto S-CG, Amorim FF, Viscardi RC. Correlation of the EuroSCORE with the onset of postoperative acute kidney injury in cardiac surgery. Rev Bras Ter intensiva [Internet]. 2013;25(3):233–8
dc.sourceVargas JG, Rodríguez MP, García PK, Ruiz Á. Predicción de aparición de injuria renal aguda después de cirugía cardiovascular en la unidad de cuidados intensivos del Hospital Universitario San Ignacio. Acta Medica Colomb [Internet]. 2010;166– 74.
dc.sourceGuerrero A, Camacho J, Sandoval N, Umaña J, Obando C. Factores asociados a insuficiencia renal postoperatoria en cirugía de revascularización miocárdica. Rev Colomb Cardiol. 2016;23(3):230–6.
dc.sourceThakar C V., Yared JP, Worley S, Cotman K, Paganini EP. Renal dysfunction and serious infections after open-heart surgery. Kidney Int. 2003;64(1):239–46.
dc.sourceOf-Official Journal Onal Society, Group KDIGO (KDIGO) CW. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int Suppl [Internet]. 2013;3(1):4–4.
dc.sourceBellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care [Internet]. 2004;8(4):R204-12.
dc.sourceMehta RL, Kellum JA, Shah S V., Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care [Internet]. 2007;11(2):R31.
dc.sourceBastin AJ, Ostermann M, Slack AJ, Diller GP, Finney SJ, Evans TW. Acute kidney injury after cardiac surgery according to Risk/Injury/Failure/Loss/End-stage, Acute Kidney Injury Network, and Kidney Disease: Improving Global Outcomes classifications. J Crit Care. Elsevier Inc.; 2013;28(4):389–96.
dc.sourceLassnigg A. Minimal Changes of Serum Creatinine Predict Prognosis in Patients after Cardiothoracic Surgery: A Prospective Cohort Study. J Am Soc Nephrol [Internet]. 2004;15(6):1597–605.
dc.sourcePatel UD, Garg AX, Krumholz HM, Shlipak MG, Coca SG, Sint K, et al. Preoperative serum brain natriuretic peptide and risk of acute kidney injury after cardiac surgery. Circulation. 2012;125(11):1347–55.
dc.sourceKarkouti K, Wijeysundera DN, Yau TM, McCluskey S a., Chan CT, Wong P-Y, et al. Influence of Erythrocyte Transfusion on the Risk of Acute Kidney Injury after Cardiac Surgery Differs in Anemic and Nonanemic Patients. Anesthesiology. 2011;115(3):523–30.
dc.sourceDe Santo L, Romano G, Della Corte A, de Simone V, Grimaldi F, Cotrufo M, et al. Preoperative anemia in patients undergoing coronary artery bypass grafting predicts acute kidney injury. J Thorac Cardiovasc Surg. The American Association for Thoracic Surgery; 2009;138(4):965–70.
dc.sourceNangaku M. Chronic Hypoxia and Tubulointerstitial Injury : A Final Common Pathway to End-Stage Renal Failure. 2006;17–25.
dc.sourceHaase M, Bellomo R, Story D, Letis A, Klemz K, Matalanis G, et al. Effect of mean arterial pressure, haemoglobin and blood transfusion during cardiopulmonary bypass on post-operative acute kidney injury. Nephrol Dial Transplant. 2012;27(1):153–60.
dc.sourceKoch CG, Li L, Sessler DI, Figueroa P, Hoeltge GA, Mihaljevic T, et al. Duration of Red-Cell Storage and Complications after Cardiac Surgery. N Engl J Med [Internet]. 2008;358(12):1229–39.
dc.sourceHalkos ME, Puskas JD, Lattouf OM, Kilgo P, Kerendi F, Song HK, et al. Elevated preoperative hemoglobin A1c level is predictive of adverse events after coronary artery bypass surgery. J Thorac Cardiovasc Surg. 2008;136(3):631–40.
dc.sourceHudson CCC, Welsby IJ, Phillips-Bute B, Mathew JP, Lutz A, Chad Hughes G, et al. Glycosylated hemoglobin levels and outcome in non-diabetic cardiac surgery patients. Can J Anaesth. 2010;57(6):565–72.
dc.sourceCortina Romero JM. Condiciones de aplicación de modelos de riesgo en cirugía cardiaca. Rev Española Cardiol [Internet]. 2008;61(6):567–71.
dc.sourceNigwekar SU, Kandula P, Hix JK, Thakar C V. Off-Pump Coronary Artery Bypass Surgery and Acute Kidney Injury: A Meta-analysis of Randomized and Observational Studies. Am J Kidney Dis [Internet]. Elsevier Inc.; 2009;54(3):413– 23.
dc.sourcePaparella D, Yau TM, Young E. Cardiopulmonary bypass induced inflammation: Pathophysiology and treatment. An update. Eur J Cardio-thoracic Surg. 2002;21(2):232–44.
dc.sourcePresta P, Onorati F, Fuiano L, Mastroroberto P, Santarpino G, Tozzo C, et al. Can pulsatile cardiopulmonary bypass prevent perioperative renal dysfunction during myocardial revascularization in elderly patients? Nephron - Clin Pract. 2009;111(4):229–36.
dc.sourceRiou B, Ph D, Kumar AB, Suneja M. Cardiopulmonary Bypass – associated Acute Kidney Injury. Anesthesiology. 2011;114(4):964–70.
dc.sourceShroyer AL, Grover FL, Hattler B, Collins JF, McDonald GO, Kozora E, et al. On- Pump versus Off-Pump Coronary-Artery Bypass Surgery. N Engl J Med. 2009;361(19):557–68.
dc.sourceSabik JF, Gillinov AM, Blackstone EH, Vacha C, Houghtaling PL, Navia J, et al. Does off-pump coronary surgery reduce morbidity and mortality? J Thorac Cardiovasc Surg. 2002;124(4):698–707.
dc.sourceJorge-Monjas P, Bustamante-Munguira J, Lorenzo M, Heredia-Rodríguez M, Fierro I, Gómez-Sánchez E, et al. Predicting cardiac surgery-associated acute kidney injury: The CRATE score. J Crit Care [Internet]. Elsevier B.V.; 2016;31(1):130–8.
dc.sourceLi-jun S, Cheng X, Hai-peng S. Relationship of pre-operative serum brain natriuretic peptide with risk of acute kidney injury after cardiac surgery. Acad J Sec Mil Med Univ. 2015;36(5):560–3.
dc.sourceMoguel-González M, Wasung-de-Lay M, Tella-Vega P, Riquelme-Mc-Loughlin C, Villa AR, Madero M, et al. Acute kidney injury in cardiac surgery. Rev Investig Clin. 2013;65(6):467–75.
dc.sourceAnghel D, Anghel R, Corciova F, Enache M, Tinica G. Preoperative arrhythmias such as atrial fibrillation: Cardiovascular surgery risk factor. Biomed Res Int. Hindawi Publishing Corporation; 2014;2014(January 2000).
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectLesión renal aguda
dc.subjectEuroSCORE
dc.subjectCirculación extracorpórea
dc.subjectCirugía cardiaca
dc.titleFactores asociados a lesión renal aguda en pacientes sometidos a cirugía cardiaca en la Fundación Cardioinfantil
dc.typemasterThesis


Este ítem pertenece a la siguiente institución