Relación entre atrofia cortical difusa y desempeño cognitivo : estudio en población mayor de 60 años en un hospital universitario en la ciudad de Bogotá

Abstract

The objective of this study was to evaluate if there is a relationship between diffuse cortical atrophy objectified by cerebral neuroimages and cognitive performances determined by the application of neuropsychological tests that evaluate working memory, verbal symbolic reasoning and declarative anterograde memory. 114 participants were recruited at the Hospital Universitario Mayor Méderi of Bogotá through a convenience sample. The results showed significant differences between the two groups (patients with diagnosis of diffuse cortical atrophy and patients with neuroimages interpreted as within normal limits) in al applied neuropsychological tests. Regarding the demographic variables, it was observed that the level of schooling contributes as a neuroprotective factor of a possible cognitive impairment. Such findings are important in determining early protocols for the detection of possible primary neurodegenerative diseases.