Estudio de correlación entre la PaO2/FiO2 y la SO2/FiO2 en niños en ventilación mecánica de la Fundación Cardioinfantil en Bogotá entre Abril y Junio de 2011

Abstract

Objectives: To determine if there is any correlation between SaFiO2 and PaFiO2 variables of patients with acute respiratory disease in the Pediatric Intensive Care Unit in Fundacion Cardioinfantil the city of Bogotá DC. Materials and methods: The quantitative variables were analyzed with measures of central tendency like average and measures of dispersion such as standard deviation. We used a confidence level of 95% and an estimated 80% power to test hypotheses of a proportion. We performed a correlation analysis to measure the strength of the relation between PaO2/FiO2 and SO2/FiO2 variables through the coefficient of correlation. Results: We included 12 patients and it took a total of 65 records of SO2/FiO2 and PaO2/FiO2 founding a positive relation between SaO2/FIO2 and PaO2/FIO2 variables, which is variable depending on the inspired fraction of oxygen to which is the patient. According to the observations, the SaO2/FIO2 variable is moderately correlated (r = 0.602) with PaO2/FIO2 variable, when FIO2 is between 0.35 and 0.55, one degree of acceptable correlation (r = 0.319), when the FIO2 is between 0.60 to 0.80 and 0.81 - 1 (r = 0.318). Conclusions: The noninvasive methods in the evaluation of oxygenation may be an alternative for clinical monitoring in children with acute lung injury or acute respiratory distress syndrome. It requires an analytical studies to provide a better scientific evidence which can be extrapolated to the children covered by this study.