Factores asociados a la infección para Clostridium difficile en un hospital universitario de Bogotá

Abstract

Introduction Infection with Clostridium difficile , is one of the most common causes of nosocomial diarrhea with high morbidity and mortality , with an exponential increase in incidence in the United States doubled from 261 cases per 100,000 in 1993 to 546 per 100,000 spent in 2003 2 , and Canada Similar data were found with increased 4.5 times in 1991 to 35.6 cases per 100,000 to 156.3 per 100,000 in 2004 3. Described several factors associated. Materials and Methods This is a descriptive study of case series in which patients with diagnosis of C. difficile infection and associated factors in a University Hospital from February 2010 to September 2011 Results 31 patients were collected , the average age was 58 years, ranging between 18 and 93 years, of which 19 ( 61 %) were women and 12 ( 39 %) men. The factor associated with C. difficile infection most frequently found was the use of proton pump inhibitors with 54.84 % (n = 17). No HIV positive or diagnosed with inflammatory bowel disease patients were found. No patient had complications from infection or some mortality . Conclusion The factor most associated was presented was the use of antimicrobials in the box before the start of the 74 % of patients which is consistent with what was presented in the literatura.