masterThesis
Incidencia y factores asociados a infecciones bacterianas en el primer mes postrasplante hepático en la Fundación Cardioinfantil
Fecha
2016Autor
Daza Buitrago, Jorge
Institución
Resumen
Introduction: orthotropic liver transplantation is the placement of a new
liver in the same location of the explanted. The goal is to extend the life
and quality of life in patients with terminal liver disease. However,
bacterial infections are a complication in transplant recipient patients,
compromising the success of the procedure. The objective was to
determine the factors associated with bacterial infections in the first
month after the intervention performed and describe the demographic
characteristics of this population. 332 transplants, 262 met the criteria
for analysis.
Methods: An analytical observational studies and nested in a cohort, in
over 18 years, primary liver transplant recipients, the FCI-IC 2005-
2014 controls was performed; excluding combined liver kidney
transplantation, retransplantation or death caused by different infectious
during the first month.
Results: It was found that mechanical ventilation for more than one
day, the largest central venous catheter three days are the main risk
factors for bacterial infections. Most 2,6gr albumin / dL was associated
with lower infection. The predominant etiologic agents were gramnegative
bacteria such as E. coli, K. pneumoniae and E. cloacae. While
bacteremia, urinary tract infection and peritonitis were the most
frequent infections. The incidence of bacterial infection in this
population was 24%.
Discussion: In these patients is recommended extubation within 24
hours, less use of central catheter three days and limit the use of bladder
catheter.