Factores asociados al riesgo de infecciones únicas y mixtas de Plasmodium SP. en población con sintomatología en el trapecio amazónico

dc.contributorCamargo Pinzón, Sandra Milena
dc.creatorGonzález Carreño, Zanony Alberto
dc.date.accessioned2018-06-05T17:53:35Z
dc.date.available2018-06-05T17:53:35Z
dc.date.created2018-06-05T17:53:35Z
dc.date.issued2018
dc.identifierhttp://repository.urosario.edu.co/handle/10336/18034
dc.description.abstractIntroduction: Malaria is a serious public health problem, in 2015 there were about 214 million cases and 438,000 deaths worldwide. The department of the Amazon, reports higher indicators, where the cases with greater frequency are attributed to P. vivax 61.4%, followed by P. malariae 43.8% and lower percentage P. falciparum 11.8%. Objective: To determine the sociodemographic, clinical and housing factors that are associated with the risk of single and mixed infections by Plasmodium spp. in the municipalities of Leticia and Puerto Nariño. Methodology: Cross-sectional analytical observational study; database with secondary information, Analysis of sociodemographic, clinical and housing factors related to the prevalence of Plasmodium spp. Descriptive analysis, multiple correspondence analysis and binary logistic regression. Results: 50.8% of people with symptoms associated with malaria were men. Associations between zone 1 and mixed infection P. vivax and P. malariae (aOR 2.13: 1.33-3.42 95% CI); access to water service with mixed infections by P. malariae and P. falciparum (aOR 6.90: 4.98-8.28 95% CI) and triple infections (aOR 3.05: 1.20-7.74 95% CI), fever with triple infection (aOR 2.91 : 1.55-4.14 95% CI). Lower association parasitaemia (5,000 to 9,999 parasites / μL blood) in P. malariae and P. falciparum (ORaj 0.18: 0.35-0.93 95% CI). Conclusions: Public health actions and strategies should focus on housing variables and clinics, due to their relation to the risk of Plasmodium spp. the study evidences the underreporting of mixed infections by Plasmodium spp., which occur in endemic area for malaria of the Amazonian trapeze.
dc.languagespa
dc.publisherUniversidad del Rosario
dc.publisherMaestría en Epidemiología
dc.publisherFacultad de medicina
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAbierto (Texto Completo)
dc.rightsEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.sourceWHO. World Malaria Report. World Health Organization. Geneva, Switzerland. 2016.
dc.sourceWhite NJ, Pukrittayakamee S, Hien TT, Faiz MA, Mokuolu OA, Dondorp AM. Malaria. The Lancet. 2014;383(9918):723-35.
dc.sourceArria Mea. Ecoepidemiologia de las enfermedades tropicales en países de la cuenca amazónica. Perú Med Exp Salud Pública. 2005;22(3).
dc.sourcePineda FYea. Evaluación del Programa de Control de la Malaria en la Amazonía Colombiana. Salud Pública. 2004;6 (Sup. 1):40-9.
dc.sourceOPS/OMS. Alerta Epidemiológica: Aumento de casos de malaria, 15 de febrero de 2017. Washington, D.C. 2017.
dc.sourcePAHO/WHO. Report on the Situation of Malaria in the Americas, 2000-2015. 2017.
dc.sourcePAHO. Report on the situation of malaria in the Americas 2012. Panamerican Health Organization. 2013.
dc.sourceArevalo-Herrera Mea. Malaria in selected non-Amazonian countries of Latin America. Acta tropica 2012;121(doi:10.1016/j.actatropica.2011.06.008):303-14.
dc.sourceCarebilla MA. Plan de Desarrollo Amazonas 2016-2019. Gestión y Ejecución para el Bienestar, la Conservación Ambiental y la Paz. Amazonas Dd, editor. Leticia - Amazonas2015.
dc.sourceAmazonas FIdIdC-FaGd. Estrategias de prevención y control de malaria en el Amazonas, en respuesta al reciente brote de la enfermedad. 2015.
dc.sourceBoletín Epidemiologico: Vigilancia de la malaria en Colombia. Boletín. 2010 SE 49.
dc.sourceRodrigues JC UG, Araújo RM, Narváez PC, Valencia SH. Epidemiology and control of malaria in Colombia. 2011.
dc.sourcePoveda GWR. Evidencias de la asociación entre brotes epidemicos de malaria en Colombia y el fenómeno del niño-oscilación del sur. Revista de la Academia Colombiana de Ciencias 1997 21(81):421-9.
dc.sourceDelgado LC, K. and Rodríguez, A. Utilidad de los sensores remotos climáticos en la prevención y diagnóstico de condiciones ambientales asociadas a la dinámica de enfermedades tropicales: la malaria en el estado de Sucre, Venezuela. 2006.
dc.sourceSalud. OPdlSOMdl. Alerta Epidemiológica aumento de casos de malaria.15 de febrero de 2017. 2017.
dc.sourceWHO. Malaria entomology and vector control. World Health Organization Geneva, Switzerland. 2015;32.
dc.sourceValle DaT, J.M. Large-scale drivers of malaria and priority areas for prevention and control in the Brazilian Amazon region using a novel multi-pathogen geospatial model. Malaria Journal. 2014;13:1-13.
dc.sourceda Silva NSea. Epidemiology and control of frontier malaria in Brazil: lessons from community-based studies in rural Amazonia. The American Society of Tropical Medicine and Hygiene. 2010;104(doi:10.1016/j.trstmh.2009.12.010):343-50.
dc.sourceGodfray HC. Mosquito ecology and control of malaria. Journal of Animal Ecology. 2013;82:15-25.
dc.sourceAnyanwu PE, Fulton, J., Evans, E. & Paget, T. Exploring the role of socioeconomic factors in the development and spread of anti-malarial drug resistance: a qualitative study. Malaria Journal. 2017;16:1-15.
dc.sourceFerreira MU, Castro MC. Challenges for malaria elimination in Brazil. Malar J. 2016;15(1):284.
dc.sourceda Silva-Nunes Mea. Amazonian malaria: asymptomatic human reservoirs, diagnostic challenges, environmentally-driven changes in mosquito vector populations, and the mandate for sustainable control strategies. Acta Tropical. 2012;121(3)(doi:10.1016/j.actatropica.2011.10.001):281-91.
dc.sourcePérez Lea. La malaria en el Amazonas conocimientos, prácticas, prevalencia de parasitemia y evaluación entomológica en mayo de 1997. Biomédica. 1999;19(2):93-102.
dc.sourceHivat H, Bretas, G. Ecology of Anopheles darlingi root with respect to vector importance. Parasit Vectors. 2011;4(177).
dc.sourceal. UNdCSAe. Hacia un CONPES INDÍGENA amazónico: construyendo una política pública integral para los pueblos indígenas de la Amazonia colombiana. Zárate CG, editor2012.
dc.sourceBarthem R, Charvet, A., Montag, L., & Lanna, A. Global interntiional waters assessment. Amazon Basin. 2004.
dc.sourceHiwat HaB, G. Ecology of Anopheles darlingi root with respect to vector importance. Parasites & Vectores. 2011;4:1-13.
dc.sourceTadei WP, Thatcher BD, Santos JM, Scarpassa VM, Rodrigues IB, Rafael MS. Ecologic observations on anopheline vectors of malaria in the Brazilian Amazon. The American Journal of Tropical Medicine and Hygiene. 1998;59(2):325-35.
dc.sourceConfalonieri UE, Margonari, C. and Quintao, A. F. Environmental change and the dynamics of parasitic diseases in the Amazon. Acta Tropica. 2014;129:33-41.
dc.sourceal. TWe. Effect of environmental change on malaria in the amazon region of brazil. Wagenigen: UR Frontis. 2005:págs. 113-23).
dc.sourceOlson SHea. Links between Climate, Malaria, and Wetlands in the Amazon Basin. Emerging Infectious Diseases. 2009;15(4):659-62.
dc.sourceDelgado Lea. Utilidad de los sensores remotos climáticos en enfermedades tropicales. 2004.
dc.sourceOsborn Fea. Caracterización Ecoregional de los Vectores de Malaria en Venezuela. Boletín de Malariologia y Salud Ambiental. 2004.
dc.sourceBannister-Tyrrell M, Verdonck K, Hausmann-Muela S, Gryseels C, Muela Ribera J, Peeters Grietens K. Defining micro-epidemiology for malaria elimination: systematic review and meta-analysis. Malar J. 2017;16(1):164.
dc.sourceAnyanwu PE, Fulton J, Evans E, Paget T. Exploring the role of socioeconomic factors in the development and spread of anti-malarial drug resistance: a qualitative study. Malaria journal. 2017;16(1):203.
dc.sourceDriss A, Hibbert JM, Wilson NO, Iqbal SA, Adamkiewicz TV, Stiles JK. Genetic polymorphisms linked to susceptibility to malaria. Malaria journal. 2011;10:271.
dc.sourceGutierrez JB, Galinski MR, Cantrell S, Voit EO. From within host dynamics to the epidemiology of infectious disease: Scientific overview and challenges. Mathematical biosciences. 2015;270(Pt B):143-55.
dc.sourceNino CH, Cubides JR, Camargo-Ayala PA, Rodriguez-Celis CA, Quinones T, Cortes-Castillo MT, et al. Plasmodium malariae in the Colombian Amazon region: you don't diagnose what you don't suspect. Malaria journal. 2016;15(1):576.
dc.sourceSingh US, Siwal N, Pande V, Das A. Can Mixed Parasite Infections Thwart Targeted Malaria Elimination Program in India? BioMed research international. 2017;2017:2847548.
dc.sourceZimmerman PA, Mehlotra RK, Kasehagen LJ, Kazura JW. Why do we need to know more about mixed Plasmodium species infections in humans? Trends in parasitology. 2004;20(9):440-7.
dc.sourceSinghanetra-Renard A. Population movement, socio-economic behavior and the transmission of malaria in northern Thailand. Southeast Asian J Trop Med Public Health. 1986;17(3):396-405.
dc.sourceIjumba JNea. Malaria transmission risk variations derived from different agricultural practices in an irrigated area of northern Tanzania. Medical and Veterinary Entomology. 2002;16:28-38.
dc.sourceKazembe LN, Mathanga DP. Estimating risk factors of urban malaria in Blantyre, Malawi: A spatial regression analysis. Asian Pacific Journal of Tropical Biomedicine. 2016;6(5):376-81.
dc.sourceKonradsen Fea. Strong association between house characteristics and malaria vectors in Sri Lanka. The American Society of Tropical Medicine and Hygiene. 2003;68(2):177-81.
dc.sourceButraporn P, Sornmani S, Hungsapruek T. Social, behavioural, housing factors and their interactive effects associated with malaria occurrence in east Thailand. Southeast Asian J Trop Med Public Health. 1986;17(3):386-92.
dc.sourceGuthmann JPea. Environmental factors as determinants of malaria risk. A descriptive study on the northern coast of Peru. Tropical Medicine and International Health. 2002;7(6):518-25.
dc.sourceal. DMGe. Factores de riesgo de Malaria en una región endémica de Sri Lanka.pdf. Medicina Tropical. 1998;5:533-42.
dc.sourceel Samani FZ, Willett WC, Ware JH. Nutritional and socio-demographic risk indicators of malaria in children under five: a cross-sectional study in a Sudanese rural community. J Trop Med Hyg. 1987;90(2):69-78.
dc.sourceVaca-Marín MA. Fatores de risco e perspectivas do controle da malaria na fronteira de Chiapas-Mexico- com Guatemala.: Instituto Oswaldo Cruz; 1994.
dc.sourceRodríguez UC, Rivera, M. and Rebaza, I. H. Factores de riesgo para Malaria por Plasmodium vivax en una población rural de Trujillo, Perú. Rev Perú Med Exp Salud Pública. 2007;24(1):35-9.
dc.sourceOsorio Lea. Travel histories as risk factors in the analysis of urban malaria in Colombia. The American Society of Tropical Medicine and Hygiene. 2004;71(4):380-6.
dc.sourceCamargo-Ayala ea. High Plasmodium malariae Prevalence in an Endemic Area of the Colombian Amazon Region. PloS one 11, e0159968, doi:101371/journalpone0159968. 2016.
dc.sourcePerú. MdSd. Manual de procedimientos de laboratorio para el diagnóstico de malaria. Serie de Normás Técnicas. 2003;39:1-112.
dc.sourceINS O, MSPS. Guía para la atención clínica integral del paciente con malaria. 2010.
dc.sourceTakken Wea. Effect of environmental change on malaria in the amazon region of brazil. 2005.
dc.sourceSalud INd. Protocolo de Vigilancia en Salud Pública - Malaria. 2016.
dc.sourceAlger J. Diagnóstico Microscópico de la malaria gota gruesa y extendido fino. Rev Med Hond. 1999;67:216-8.
dc.sourceNiño CH, Cubides JR, Camargo-Ayala PA, Rodríguez-Celis CA, Quiñones T, Cortés-Castillo MT, et al. Plasmodium malariae in the Colombian Amazon region: you don’t diagnose what you don’t suspect. Malaria Journal. 2016;15(1).
dc.sourceMendoza NMea. Diagnóstico de malaria por el método de la PCR anidada. Biomédica. 2001;21:320 - 7.
dc.sourceCowman AF, Healer J, Marapana D, Marsh K. Malaria: Biology and Disease. Cell. 2016;167(3):610-24.
dc.sourceLalremruata A, Jeyaraj S, Engleitner T, Joanny F, Lang A, Belard S, et al. Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing. Malar J. 2017;16(1):398.
dc.sourceOguike MCea. Plasmodium ovale curtisi and Plasmodium ovale wallikeri circulate simultaneously in African communities. International journal for parasitology 2011;41(doi:10.1016/j.ijpara.2011.01.004. ):677-83.
dc.sourceInstituto Nacional de Salud Protocolo de vigilancia en salud pública de la malaria2016.
dc.sourceTobón CAea. Clínica de la malaria complicada debida a P. falciparum Estudio de casos y controles en Tumaco y Turbo - Colombia. IATREIA. 2006;19(4):339-55.
dc.sourceTobón A. Signos de peligro en pacientes con malaria.pdf. Biomédica. 2009;29:320-9.
dc.sourceDANE. Estimaciones de Población para Colombia 1985 - 2005 y Proyecciones de Población 2005 - 2020. . Información estadística DANE. 2005:1-193.
dc.sourcePhillips MA, Burrows JN, Manyando C, van Huijsduijnen RH, Van Voorhis WC, Wells TNC. Malaria. Nature reviews Disease primers. 2017;3:17050.
dc.sourceCarmona-Fonseca J, Arango Flórez E. Mixed malaria: Prevalence in Colombia and Latin America2012. 334-46 p.
dc.sourceGalvis FS. PCR anidada y PCR convencional en el diagnóstico de Plasmodium vivax y P. falciparum. Bistua: Revista de la Facultad de Ciencias Básicas. 2013;11(1):21 - 8.
dc.sourceCollins WEJ, G. M. Plasmodium malariae: parasite and disease. Clinical microbiology reviews. 2007;20(doi:10.1128/CMR.00027-07):579-92.
dc.sourceDel Rio-Ospina L, Soto-De Leon SC, Camargo M, Sanchez R, Moreno-Perez DA, Perez-Prados A, et al. Multiple high-risk HPV genotypes are grouped by type and are associated with viral load and risk factors. Epidemiology and infection. 2017;145(7):1479-90.
dc.sourceLebart L, Morineau A, Piron M. Statistique Exploratoire Multidimensionnelle. Paris: Dunod1995. 439 p.
dc.sourceEscofier B, Pagés J. Análisis factoriales simples y múltiples: objetivos, métodos e interpretación. España: Universidad del País Vasco1992. 286 p.
dc.sourceLey Estatutaria Habeas Data, Pub. L. No. 1266 del 31 de diciembre(2008).
dc.sourceConstitución Política de Colombia. Asamblea General Constitucional. Colombia 1991., Stat. Titulo II. Capitulo I. Art. 15. pág. 2. (1991).
dc.sourceDeclaración de Helsinki: principios éticos para la investigación médica sobre sujetos humanos. Acta bioethica. 2000;6:321-34. , (1989).
dc.sourceInforme Belmont: Principios y guías éticos para la protección de los sujetos humanos de investigación. Comisión nacional para la protección de los sujetos humanos de investigación biomédica y del comportamiento USA., (1979).
dc.sourceResolución 8430 de octubre 4 de 1993. Por la cual se establecen las normas científicas, técnicas y administrativas para la investigación en salud., (1993).
dc.sourceLana RM, Riback TIS, Lima TFM, da Silva-Nunes M, Cruz OG, Oliveira FGS, et al. Socioeconomic and demographic characterization of an endemic malaria region in Brazil by multiple correspondence analysis. Malaria journal. 2017;16(1):397.
dc.sourceAyele D, Zewotir T, Mwambi H. Multiple correspondence analysis as a tool for analysis of large health surveys in African settings. African health sciences. 2014;14(4):1036-45.
dc.sourceBarbosa S, Gozze AB, Lima NF, Batista CL, Bastos Mda S, Nicolete VC, et al. Epidemiology of disappearing Plasmodium vivax malaria: a case study in rural Amazonia. PLoS neglected tropical diseases. 2014;8(8):e3109.
dc.sourceRecht J, Siqueira AM, Monteiro WM, Herrera SM, Herrera S, Lacerda MVG. Malaria in Brazil, Colombia, Peru and Venezuela: current challenges in malaria control and elimination. Malar J. 2017;16(1):273.
dc.sourceAlemu A, Fuehrer HP, Getnet G, Kassu A, Getie S, Noedl H. Comparison of Giemsa microscopy with nested PCR for the diagnosis of malaria in North Gondar, north-west Ethiopia. Malaria journal. 2014;13:174.
dc.sourceWangai LN, Karau MG, Njiruh PN, Sabah O, Kimani FT, Magoma G, et al. Sensitivity of microscopy compared to molecular diagnosis of p. Falciparum: implications on malaria treatment in epidemic areas in kenya. African journal of infectious diseases. 2011;5(1):1-6.
dc.sourceRodriguez JC, Uribe GA, Araujo RM, Narvaez PC, Valencia SH. Epidemiology and control of malaria in Colombia. Memorias do Instituto Oswaldo Cruz. 2011;106 Suppl 1:114-22.
dc.sourceCastellanos A, Chaparro-Narvaez P, Morales-Plaza CD, Alzate A, Padilla J, Arevalo M, et al. Malaria in gold-mining areas in Colombia. Memorias do Instituto Oswaldo Cruz. 2016;111(1):59-66.
dc.sourceCamargo-Ayala PA, Cubides JR, Nino CH, Camargo M, Rodriguez-Celis CA, Quinones T, et al. High Plasmodium malariae Prevalence in an Endemic Area of the Colombian Amazon Region. PloS one. 2016;11(7):e0159968.
dc.sourceCarrasco-Escobar G, Gamboa D, Castro MC, Bangdiwala SI, Rodriguez H, Contreras-Mancilla J, et al. Micro-epidemiology and spatial heterogeneity of P. vivax parasitaemia in riverine communities of the Peruvian Amazon: A multilevel analysis. Scientific reports. 2017;7(1):8082.
dc.sourceCollins WE, Jeffery GM. Plasmodium malariae: parasite and disease. Clinical microbiology reviews. 2007;20(4):579-92.
dc.sourceLalremruata A, Magris M, Vivas-Martinez S, Koehler M, Esen M, Kempaiah P, et al. Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon. EBioMedicine. 2015;2(9):1186-92.
dc.sourceFandeur T, Volney B, Peneau C, de Thoisy B. Monkeys of the rainforest in French Guiana are natural reservoirs for P. brasilianum/P. malariae malaria. Parasitology. 2000;120 ( Pt 1):11-21.
dc.sourceFuentes-Ramirez A, Jimenez-Soto M, Castro R, Romero-Zuniga JJ, Dolz G. Molecular Detection of Plasmodium malariae/Plasmodium brasilianum in Non-Human Primates in Captivity in Costa Rica. PloS one. 2017;12(1):e0170704.
dc.sourceLo E, Yewhalaw D, Zhong D, Zemene E, Degefa T, Tushune K, et al. Molecular epidemiology of Plasmodium vivax and Plasmodium falciparum malaria among Duffy-positive and Duffy-negative populations in Ethiopia. Malaria journal. 2015;14:84.
dc.sourceCollins WE, Jeffery GM. A retrospective examination of sporozoite- and trophozoite-induced infections with Plasmodium falciparum in patients previously infected with heterologous species of Plasmodium: effect on development of parasitologic and clinical immunity. The American journal of tropical medicine and hygiene. 1999;61(1 Suppl):36-43.
dc.sourcePombo DJ, Lawrence G, Hirunpetcharat C, Rzepczyk C, Bryden M, Cloonan N, et al. Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. Lancet. 2002;360(9333):610-7.
dc.sourceMehlotra RK, Lorry K, Kastens W, Miller SM, Alpers MP, Bockarie M, et al. Random distribution of mixed species malaria infections in Papua New Guinea. The American journal of tropical medicine and hygiene. 2000;62(2):225-31.
dc.sourceBruce MC, Day KP. Cross-species regulation of malaria parasitaemia in the human host. Current opinion in microbiology. 2002;5(4):431-7.
dc.sourceArevalo-Herrera M, Lopez-Perez M, Medina L, Moreno A, Gutierrez JB, Herrera S. Clinical profile of Plasmodium falciparum and Plasmodium vivax infections in low and unstable malaria transmission settings of Colombia. Malar J. 2015;14:154.
dc.sourceTriana-Moreno LA, Rodríguez NC, García J. Chagras’ agroforestal system dynamics as the basis for indigenous production in the Amazonian Trapezium (Colombia). Agronomía Colombiana. 2006;24(1):158-69.
dc.sourceBruce MC, Day KP. Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea. Trends in parasitology. 2003;19(6):271-7.
dc.sourceBruce MC, Donnelly CA, Alpers MP, Galinski MR, Barnwell JW, Walliker D, et al. Cross-species interactions between malaria parasites in humans. Science. 2000;287(5454):845-8.
dc.sourceGurarie D, Zimmerman PA, King CH. Dynamic regulation of single- and mixed-species malaria infection: insights to specific and non-specific mechanisms of control. Journal of theoretical biology. 2006;240(2):185-99.
dc.sourceZimmerman PA, Ferreira MU, Howes RE, Mercereau-Puijalon O. Red blood cell polymorphism and susceptibility to Plasmodium vivax. Advances in parasitology. 2013;81:27-76.
dc.sourceLawaly YR, Sakuntabhai A, Marrama L, Konate L, Phimpraphi W, Sokhna C, et al. Heritability of the human infectious reservoir of malaria parasites. PloS one. 2010;5(6):e11358.
dc.sourceQuin JE, Bujila I, Cherif M, Sanou GS, Qu Y, Vafa Homann M, et al. Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria. eLife. 2017;6.
dc.sourceMehlotra RK, Kasehagen LJ, Baisor M, Lorry K, Kazura JW, Bockarie MJ, et al. Malaria infections are randomly distributed in diverse holoendemic areas of Papua New Guinea. The American journal of tropical medicine and hygiene. 2002;67(6):555-62.
dc.sourceBruce MC, Macheso A, McConnachie A, Molyneux ME. Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi. Malaria journal. 2011;10:38.
dc.sourceMcKenzie FE, Bossert WH. Mixed-species Plasmodium infections of humans. The Journal of parasitology. 1997;83(4):593-600.
dc.sourceChiyaka C, Mukandavire Z, Das P, Nyabadza F, Hove-Musekwa SD, Mwambi H. Theoretical analysis of mixed Plasmodium malariae and Plasmodium falciparum infections with partial cross-immunity. Journal of theoretical biology. 2010;263(2):169-78.
dc.sourceZhou M, Liu Q, Wongsrichanalai C, Suwonkerd W, Panart K, Prajakwong S, et al. High prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai-Myanmar border, as revealed by acridine orange staining and PCR-based diagnoses. Tropical medicine & international health : TM & IH. 1998;3(4):304-12.
dc.sourceCavasini MT, Ribeiro WL, Kawamoto F, Ferreira MU. How prevalent is Plasmodium malariae in Rondonia, western Brazilian Amazon? Revista da Sociedade Brasileira de Medicina Tropical. 2000;33(5):489-92.
dc.sourceBruce MC, Macheso A, Galinski MR, Barnwell JW. Characterization and application of multiple genetic markers for Plasmodium malariae. Parasitology. 2007;134(Pt 5):637-50.
dc.sourceBruce MC, Macheso A, Kelly-Hope LA, Nkhoma S, McConnachie A, Molyneux ME. Effect of transmission setting and mixed species infections on clinical measures of malaria in Malawi. PloS one. 2008;3(7):e2775.
dc.sourceOstfeld RS, Glass GE, Keesing F. Spatial epidemiology: an emerging (or re-emerging) discipline. Trends in ecology & evolution. 2005;20(6):328-36.
dc.sourceStresman GH, Giorgi E, Baidjoe A, Knight P, Odongo W, Owaga C, et al. Impact of metric and sample size on determining malaria hotspot boundaries. Scientific reports. 2017;7:45849.
dc.sourceBousema T, Drakeley C, Gesase S, Hashim R, Magesa S, Mosha F, et al. Identification of hot spots of malaria transmission for targeted malaria control. The Journal of infectious diseases. 2010;201(11):1764-74.
dc.sourceBousema T, Griffin JT, Sauerwein RW, Smith DL, Churcher TS, Takken W, et al. Hitting hotspots: spatial targeting of malaria for control and elimination. PLoS medicine. 2012;9(1):e1001165.
dc.sourceValle D, Lima JM. Large-scale drivers of malaria and priority areas for prevention and control in the Brazilian Amazon region using a novel multi-pathogen geospatial model. Malaria journal. 2014;13:443.
dc.subjectMalaria
dc.subjectTrapecio Amazónico
dc.subjectPrevalencia
dc.subjectAsociación
dc.subjectDemográficas
dc.subjectCorrespondencias múltiples
dc.subjectInfecciones mixtas
dc.subjectEstudio transversal
dc.subjectPlasmodium spp
dc.titleFactores asociados al riesgo de infecciones únicas y mixtas de Plasmodium SP. en población con sintomatología en el trapecio amazónico
dc.typemasterThesis


Este ítem pertenece a la siguiente institución