masterThesis
Manifestaciones clínicas y radiológicas de los pacientes con tuberculosis con y sin diabetes mellitus
Fecha
2018Autor
Botero-Ospina, María-Helena
Espinosa, Juan Sebastian
Institución
Resumen
Introduction: Patients diagnosed with tuberculosis (TB) and diabetes mellitus (DM) may have a different clinical course than patients without DM. However, uncertainty persists about this relationship. Objective: To describe and compare the clinical radiological findings in patients diagnosed with Tuberculosis, with and without diabetes mellitus at a university hospital
Methods: Cross-sectional trial of patients diagnosed with TB managed in the university hospital. Information was collected about sociodemographic, clinical, loboratory, X-ray and outcome data of the patients for five years (2012 to 2016). Univariate and then bivariate descriptive statistics were used to present the distribution of the characteristics of the patients due to the presence or absence of DM. The existence of differences between controlled and uncontrolled diabetic patients was explored (glycosylated hemoglobin <7% was defined as a controlled patient), calculating prevalence ratios of relevant variables. Results: 221 patients with TB were included, of which 32 had DM (14.48%). Median age was 66 years (Q1 48; Q3 76). Patients with TB/ DM were older in age, with a higher prevalence of hypertension and chronic kidney disease (p = 0.005). Among the patients with DM, uncontrolled patients had a higher prevalence of abandonment of anti-TB treatment (p = 0.000). Conclusion: We found differences between patients with DM-TB vs non-DM, with a tendency of worse outcomes, longer stay in ICU and higher rate of abandonment of anti-TB treatment.