info:eu-repo/semantics/article
Minutes, days and years: molecular interactions among different scales of biological timing
Fecha
2014-01Registro en:
Golombek, Diego Andrés; Bussi, Ivana Leda; Agostino, Patricia; Minutes, days and years: molecular interactions among different scales of biological timing; The Royal Society; Philosophical Transactions of the Royal Society B: Biological Sciences; 369; 1637; 1-2014; 20120465-20120477
0962-8436
CONICET Digital
CONICET
Autor
Golombek, Diego Andrés
Bussi, Ivana Leda
Agostino, Patricia
Resumen
Biological clocks are genetically encoded oscillators that allow organisms to keep track of their environment. Among them, the circadian system is a highly conserved timing structure that regulates several physiological, metabolic and behavioural functions with periods close to 24 h. Time is also crucial for everyday activities that involve conscious time estimation. Timing behaviour in the second-to-minutes range, known as interval timing, involves the interaction of cortico-striatal circuits. In this review, we summarize current findings on the neurobiological basis of the circadian system, both at the genetic and behavioural level, and also focus on its interactions with interval timing and seasonal rhythms, in order to construct a multi-level biological clock.