Artículos de revistas
Synthesis of organotin derivatives of optically active eleven-membered macrodiolides
Fecha
2016-05-01Registro en:
Scoccia, Jimena; Gerbino, Darío César; Podestá, Julio Cesar; Synthesis of organotin derivatives of optically active eleven-membered macrodiolides; Pergamon-Elsevier Science Ltd; Tetrahedron: Asymmetry; 27; 7-8; 1-5-2016; 352-360
0957-4166
CONICET Digital
CONICET
Autor
Scoccia, Jimena
Gerbino, Darío César
Podestá, Julio Cesar
Resumen
The synthesis and the results obtained in the hydrostannation of eight new TADDOL diacrylates and methacrylates are reported. The addition of triorganotin hydrides, R3SnH, 12-14 (R = nBu, neophyl, Ph, respectively) to diesters 6-11 containing different combinations of substituents at the C-2 carbon of the dioxolane ring, led to macrocyclization products in all cases. The cyclohydrostannation of diacrylate 10 proceeded with complete diastereoselectivity. The cyclohydrostannation of diesters 33 and 34 with hydrides 12 and 14 in all cases only afforded one stannylated macrocycle.