dc.date.accessioned | 2017-04-27T18:49:33Z | |
dc.date.available | 2017-04-27T18:49:33Z | |
dc.date.created | 2017-04-27T18:49:33Z | |
dc.date.issued | 2012 | |
dc.identifier | 1420-3049 | |
dc.identifier | http://hdl.handle.net/10533/196885 | |
dc.identifier | D08I1102 | |
dc.identifier | WOS:000299535700037 | |
dc.identifier | WOS:000299535700037 | |
dc.identifier | 0 | |
dc.description.abstract | The synthesis of twenty six prenylated phenols derivatives is reported. These compounds were obtained under mild conditions via Electrophilic Aromatic Substitution (EAS) coupling reactions between phenol derivatives containing electron-donor subtituents and 3-methyl-2-buten-1-ol using BF3 center dot OEt2. Dialkylations were also produced with this method. The formation of a chroman ring by intramolecular cyclization between a sp(2) carbon from the prenyl group with the hydroxyl substituent in the ortho position occurred with some phenols. All the synthesized compounds were evaluated as antioxidants according to a DPPH radical scavenging activity assay. IC50 values of five synthesized compounds indicated they were as good antioxidants as Trolox (TM). | |
dc.language | ENG | |
dc.publisher | MDPI AG | |
dc.relation | https://doi.org/10.3390/molecules17010556 | |
dc.relation | 10.3390/molecules17010556 | |
dc.relation | info:eu-repo/grantAgreement/Fondef/D08I1102 | |
dc.relation | info:eu-repo/semantics/dataset/hdl.handle.net/10533/93477 | |
dc.relation | instname: Conicyt | |
dc.relation | reponame: Repositorio Digital RI2.0 | |
dc.relation | instname: Conicyt | |
dc.relation | reponame: Repositorio Digital RI2.0 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.title | Synthesis and dpph radical scavenging activity of prenylated phenol derivatives | |
dc.type | Articulo | |