Artículos de revistas
Disarray Of Glomerular And Tubular Cell Adhesion Molecules In The Course Of Experimental Bothrops Moojeni Envenomation.
Registro en:
Toxicon : Official Journal Of The International Society On Toxinology. v. 78, p. 41-6, 2014-Feb.
1879-3150
10.1016/j.toxicon.2013.11.013
24291462
Autor
Collares-Buzato, Carla Beatriz
da Cruz-Höfling, Maria Alice
Institución
Resumen
In this study, we show that administration of Bothrops moojeni venom in rats induces a general disturbance in the distribution and content of the tight junctional protein ZO-1, the cell-matrix receptor beta 1 integrin, the cytoskeletal proteins, vinculin and F-actin, and of the extracellular matrix component laminin in renal corpuscles and cortical nephron tubules. These findings suggest that cell-cell and cell-matrix adhesion proteins may be molecular targets in the B. moojeni-induced kidney injury. 78 41-6